Food safety is an important concern that includes handling, preparation and storage of food ingredients in ways that prevent poisoning. Unhealthy food creates a cycle of disease and malnutrition that affects infants and adults as well. Foods can be contaminated by microorganisms such as bacteria, viruses, parasites or fungi. There are specific bacteria which are the primary causes of foodborne diseases; among them: Escherichia coli, Salmonella enterica, Campylobacter jejuni, Staphylococcus aureus, Listeria monocytogenes, and Bacillus cereus. These microbes might have been present before the food was harvested or collected, or they could have been introduced during handling or preparation. Pesticides and veterinary drugs introduced to protect plants and animals from pests and diseases could later unintentionally result in contamination of the food products derived from these sources (e.g. mycotoxins, heavy metals or persistent organic pollutants).

The necessity to determine pathogenic organisms and their toxins serves as a fundamental requirement to guarantee the safety and quality of our food supplies. Detection methods with enhanced sensitivity and rapid results are a prerequisite to achieve efficient tests.

Fermentek supports customers globally with a wide range of food-safety related products to ensure the integrity of customers’ needs. Our food safety testing materials can be used for determination of contaminants or toxins. Also, our test procedure can determine and quantify adulterants, hazardous chemicals or pathogens present in food that can have a dangerous influence on human health.

Food Safety Related Products

Food-safety related products produced by Fermentek include natural toxins which may occur in foodstuffs and standard "ready to use" solutions (Mycotoxin Standards) of toxins containing known accurate amounts in commonly used solvents. The standard solutions serve as quantitatively reliable samples of the toxic materials, which can be compared to tested samples of food by conventional analytical methods.

Mycotoxin Food Safety Standards

Fermentek is a global leader in the production of certified Mycotoxin reference materials for food safety labs and for R&D use. Mycotoxins are toxic fungal metabolites that may appear in food and feed as a result of fungal infection of crops such as cereals, dried fruit and many other agricultural products.

Accurate analysis of Mycotoxins depends upon the use of certified Mycotoxin standard reference materials used for calibration and validation of food safety analytical instruments and methods. High quality standards, calibrants, and reference materials are a prerequisite for valid results in any such analysis.

Among the regulated Mycotoxins offered by Fermentek are: Aflatoxin B1, B2, G1, G2, M1, M2, Aflatoxicol, Aphidicolin, Citrinin, Cytochalasin, Deoxynivalenol (DON), HT-2 toxin, Fumonisin, Fusarenon X, Gliotoxin, Nivalenol, Ochratoxin, Patulin, Sterigmatocystin, T2 Toxin, Tentoxin, and Zearalenone.

Bongkrekic acid (as solution)

Bongkrekic acid (as solution)
Molecular Formula
C28H38O7
M.W.
486.60
CAS number
11076-19-0
MSDS
Source
Pseudomonas gladioli
Fermentek product Code
BON-001
Brand/grade
For research
Appearance
Clear colorless solution
Purity by HPLC
≥95% ; refer to CoA for more data
Purity By TLC
≥98% ; refer to CoA for more data
Names and identifiers

Synonyms:

  • Bongkrekic Acid
  • Flavotoxin A

Chemical names:

IUPAC:

  • (6R,17S)-20-(carboxymethyl)-6-methoxy-2,5,17-trimethyldocosa-2,4,8,10,14,18,20-heptaenedioic acid

RTECS: JR1230000

ECHA Number: 998-673-7

EU number
Not assigned
Chemical name
Bongkrekic acid
Description

Supplied as 1mg/ml solution dissolved in 0.01M Tris buffer pH 7.5. 

InChl Key
SHCXABJSXUACKU-WUTQZGRKSA-N
Canonical SMILES
CC(CC=CCCC=CC=CCC(C(=CC=C(C)C(=O)O)C)OC)C=CC(=CC(=O)O)CC(=O)O
Isomeric SMILES
CC(C/C=C/CC/C=C/C=C\CC(/C(=C\C=C(/C)\C(=O)O)/C)OC)/C=C/C(=C\C(=O)O)/CC(=O)O
Solubility ( literature )
  • Solubility in Water: ~ 1 mg/ml
  • Solubility Notes: ~100 mg/ml in DMSO
Compound Classification
  • Chemical classification:
  • Polyunsaturated tricarboxylic acid

Bioactivity:

  • Glutathione transferase inhibitor
  • ATP/ADP translocase inhibitor
Storage, handling
Store in a freezer upon arrival, at -10°C to -25°C
Protect from light !
Open carefully.
Use the original container to store the product.
Keep the lid tightly closed.
Avoid exposing to strong direct light.
Other vendors may recommend higher temperatures for storage.
Retest time
2 Years
Applications

Bongcrekic acid is an inhibitor of adenine nucleotide translocator, which inhibits apoptosis, and is thus an important tool for the mechanistic investigation of apoptosis.

Disclaimer
For Research use only
Not for Human or Drug use
Not extracted from humans or animals
Refer to MSDS for further safety and handling instructions
Ingredient type
Fermentek product
Ingredient amount
1mg/ml in 0.01M Tris buffer pH 7.5
Shipped at ambient temperature
Shipped in PP / PE bottle.
Available since
Title
CAS ambiguity
Value
# 60132-21-0 belongs to Isobongkrekic acid . http://www.molbase.com/en/cas-60132-21-0.html
Title
oral LD50
Value
oral LD50 of the purified Flavotoxin A in mice 3.16 mg/kg
Title
More identity comments; Hu WJ et al; Biomed Environ Sci 2 (1): 65-71 (1989)
Value
Therefore, Flavotoxin A and bongkrekic acid are the same organic chemical compound; the molecular formula is C28H38O7. The oral LD50 of the purified Flavotoxin A in mice was 3.16 mg/kg (1.53-6.15 mg/kg).
Title
Deleted CAS Registry Numbers
Value
11002-93-0, 12715-13-8, 32839-39-7
Title
oral LD50
Value
ANOTHER SOURCE: MOUSE LDL0=6.85 mg/kg PMID:6391376
Signal to sort
B

Standard Solution Ochratoxin B

Standard Solution Ochratoxin B
Molecular Formula
C20H19NO6
CAS number
4825-86-9
MSDS
Fermentek product Code
STD-025
Brand/grade
Analytical standard
Names and identifiers

Synonyms:

Chemical names:

IUPAC:

RTECS#

Description

Ochratoxin B, 10 ppm in Acetonitrile "HPLC-Supra-Gradient" grade. Ready for Injection into HPLC system; Available in 1 ml or 5 ml vials.

Storage, handling
Store in a freezer upon arrival, at -10°C to -25°C
Disclaimer
For Research use only
Not for Human or Drug use
Not extracted from humans or animals
Refer to MSDS for further safety and handling instructions
Ingredient Other
Acetonitrile , HPLC grade (CAS #75-05-8)
Ingredient type
Fermentek product
Ingredient amount
to 100%
Ingredient Reference
Ingredient type
Fermentek product
Ingredient amount
10 µg/ml in Acetonitrile
Available since

Fumitremorgin C

Fumitremorgin C
Molecular Formula
C22H25N3O3
M.W.
379.46
CAS number
118974-02-0
MSDS
Source
Aspergillus sp.
Fermentek product Code
FUC-001
Brand/grade
For research
Appearance
Crystalline solid
Purity by HPLC
≥98% ; refer to CoA for more data
Purity By TLC
≥98% ; refer to CoA for more data
Solubility test
Clear colorless solution at 10mg/ml of
Methanol or Acetonitrile.
Names and identifiers

Synonyms:

Chemical names:

IUPAC:               (5aS,12S,14aS)-9-Methoxy-12-(2-methyl-1-propen-1-yl)-1,2,3,5a,6,11,12,14a-octahydro-5H,14H-pyrrolo[1'',2'':4',5']pyrazino[1',2':1,6]pyrido[3,4-b]indole-5,14-dione

RTECS#  UY8709670

EU number
Not listed
Chemical name
Fumitremorgin C
Description

Fumitremorgin C is a tremorgenic mycotoxin isolated from Aspergillus fumigatus. Recent research has recognized Fumitremorgin C as a potent and specific inhibitor of the breast cancer resistance protein (BCRP/ABCG2) multidrug transporter. It reverses multidrug resistance mediated by BCRP and increases cytotoxicity of several anticancer agents in vitro.

InChl Key
DBEYVIGIPJSTOR-FHWLQOOXSA-N
Canonical SMILES
CC(=CC1C2=C(CC3N1C(=O)C4CCCN4C3=O)C5=C(N2)C=C(C=C5)OC)C
Isomeric SMILES
CC(=C[C@H]1C2=C(C[C@@H]3N1C(=O)[C@@H]4CCCN4C3=O)C5=C(N2)C=C(C=C5)OC)C
Solubility ( literature )

Soluble in Ethanol, Methanol, DMF, DMSO Chloroform.

Negligible solubility ( 35 mg in 1 liter water @25°C) has been reported.

Compound Classification

Breast cancer resistance protein inhibitor

Mammalian cell cycle inhibitors

Storage, handling
Store in a freezer upon arrival, at -10°C to -25°C
Protect from light !
Open carefully.
Use the original container to store the product.
Keep the lid tightly closed.
Avoid exposing to strong direct light.
Other vendors may recommend higher temperatures for storage.
Retest time
3 Years
Disclaimer
For Research use only
Not for Human or Drug use
Not extracted from humans or animals
Refer to MSDS for further safety and handling instructions
Ingredient type
Fermentek product
Available since
Title
Transport information
Value
Not hazardous goods. Nor regulated
Signal to sort
F

alpha Zearalanol

alpha Zearalanol
Molecular Formula
C18H26O5
M.W.
322.40
CAS number
26538-44-3
MSDS
Source
Semisynthetic
Fermentek product Code
ZAL-001
Brand/grade
For research
Appearance
White to off white powder
Purity by HPLC
≥98% ; refer to CoA for more data
Purity By TLC
≥98% ; refer to CoA for more data
Solubility test
Clear colorless solution at 10mg/ml of Methanol
Names and identifiers

Synonyms: Zeranol; α-Zearalanol; 

Chemical names:   

IUPAC: 6-(6,10-Dihydroxyundecyl)-beta-resorcylic acid, mu-lactone;

RTECS#  DM2520000

EU number
247-769-0
Description

Alpha Zearalanol is a minor analogue of the zearalenone family of mycotoxins.

InChl Key
DWTTZBARDOXEAM-TZMCWYRMSA-N
Canonical SMILES
CC1CCCC(CCCCCC2=CC(=CC(=C2C(=O)O1)O)O)O
Isomeric SMILES
C[C@@H]1CCC[C@@H](CCCCCC2=CC(=CC(=C2C(=O)O1)O)O)O
Compound Classification

Macrolide

Mycotoxin - Zearalenone group

Fito-estrogen

 

Storage, handling
Store in a freezer upon arrival, at -10°C to -25°C
Open carefully. Use the original container to store the product.
Keep the lid tightly closed.
Applications

Phytoestrogen alpha-zearalanol  improves vascular function  in  ovariectomized  hyperhomocvsteinemic  rats. 

 

 

Disclaimer
For Research use only
Not for Human or Drug use
Not extracted from humans or animals
Refer to MSDS for further safety and handling instructions
Semi-Synthetic
Ingredient type
Fermentek product
Transport safety: Not Dangerous Goods; Not Regulated
Available since
Title
Transport information
Value
Not hazardous for transport
Title
Deleted CAS Registry Numbers
Value
5975-81-5 | 21307-30-2 | 24507-00-4 | 39487-91-7 | 40036-43-9
Signal to sort
Z

beta Zearalanol

beta Zearalanol
Molecular Formula
C18H26O5
M.W.
322.40
CAS number
42422-68-4
MSDS
Source
Semisynthetic
Fermentek product Code
ZBL-001
Brand/grade
For research
Appearance
White to off white powder
Purity by HPLC
≥98% ; refer to CoA for more data
Purity By TLC
≥98% ; refer to CoA for more data
Solubility test
Clear colorless solution at 10mg/ml of Methanol
Names and identifiers

Synonyms:          

  • Estrogen P 1560
  • Taleranol

Chemical names:

  • β- Zearalanol

IUPAC:                

  • (7S,11S)-7,15,17-trihydroxy-11-methyl-12-oxabicyclo[12.4.0]octadeca-1(14),15,17-trien-13-one

RTECS#  DM2540000

 

EU number
636-982-8
Chemical name
beta Zearalanol
Description

Beta Zearalanol, also known as taleranol, is a minor analogue of the zearalenone family of resorcinyl macrocyclic lactones, produced by several species of Fusarium. Like the other zearalenones, Beta-zearalanol exhibits estrogenic activity in animals.

 

 
InChl Key
DWTTZBARDOXEAM-JSGCOSHPSA-N
Canonical SMILES
CC1CCCC(CCCCCC2=CC(=CC(=C2C(=O)O1)O)O)O
Isomeric SMILES
C[C@H]1CCC[C@H](CCCCCC2=CC(=CC(=C2C(=O)O1)O)O)O
Storage, handling
Store in a freezer upon arrival, at -10°C to -25°C
Use the original container to store the product.
Open carefully. Keep the lid tightly closed.
Disclaimer
For Research use only
Not for Human or Drug use
Not extracted from humans or animals
Refer to MSDS for further safety and handling instructions
Semi-Synthetic
Ingredient type
Fermentek product
Title
Transport information
Value
Not hazardous for transport
Title
validations
Value
SCIFINDER formula,structure, CAS validated
Signal to sort
Z

Altertoxin I

Altertoxin I
Molecular Formula
C20H16O6
M.W.
352.34
CAS number
56258-32-3
MSDS
Source
Alternaria sp.
Fermentek product Code
ALX-001
Brand/grade
For research
Appearance
Off white to yellowish powder
Purity by HPLC
≥95% ; refer to CoA for more data
Purity By TLC
≥98% ; refer to CoA for more data
Solubility test
Clear slight yellow solution at 10mg/ml Methanol
Names and identifiers

Synonyms:

  • (12S,12As,12Br)-4,9,12,12B-Tetrahydroxy-2,11,12,12A-Tetrahydro-1H-Perylene-3,10-Quinone;
  • Altertoxin I
  • Altertoxin-I

Chemical names:

IUPAC:

  • (12S,12aS,12bR)-4,9,12,12b-tetrahydroxy-2,11,12,12a-tetrahydro-1H-perylene-3,10-dione

 

RTECS#   : BC9625200

Description

Altertoxin-1, a natural mycotoxin from Alternaria fungi, an important contaminant in cereals, vegetables.

InChl Key
GJIALGLHOBXNAT-KPOBHBOGSA-N
Canonical SMILES
C1CC2(C3C4C(O4)C(=O)C5=C(C=CC(=C35)C6=C2C(=C(C=C6)O)C1=O)O)O
Isomeric SMILES
C1C[C@]2([C@@H]3[C@H](CC(=O)C4=C(C=CC(=C34)C5=C2C(=C(C=C5)O)C1=O)O)O)O
Storage, handling
Store in a freezer upon arrival, at -10°C to -25°C
Open carefully.
Use the original container to store the product.
Keep the lid tightly closed.
Avoid exposing to strong direct light.
Other vendors may recommend higher temperatures for storage.
Retest time
3 Years
Applications

Altertoxin I (and other altertoxins) inhibit the HIV replication.

Disclaimer
For Research use only
Not for Human or Drug use
Not extracted from humans or animals
Refer to MSDS for further safety and handling instructions
Ingredient type
Fermentek product
Available since
Title
tsa
Value
V=veg fermentation
Title
classif
Value
cytotoxic; mutagenic
Signal to sort
A

Enniatin A1

Enniatin A1
Molecular Formula
C35H61N3O9
M.W.
667.87
CAS number
4530-21-6
MSDS
Source
Fusarium sp
Fermentek product Code
ENA-002
Brand/grade
For research
Appearance
White to Off-White powder
Purity by HPLC
≥98% ; refer to CoA for more data
Purity By TLC
≥98% ; refer to CoA for more data
Solubility test
Clear colorless solution at 10mg/ml of DMSO or Methanol
Names and identifiers

Synonyms:

Chemical names: Enniatin A1

IUPAC: 3S,6R,9S,12R,15S,18R)-3,9-bis[(2S)-butan-2-yl]-4,10,16-trimethyl-6,12,15,18-tetra(propan-2-yl)-1,7,13-trioxa-4,10,16-triazacyclooctadecane-2,5,8,11,14,17-hexone

IUPAC, Biological notation: cyclo[N(Me)Ile-D-OVal-N(Me)Ile-D-OVal-N(Me)Val-D-OVal]

 
EU number
215-737-5
Description

Enniatin A1 has been found to induce apoptosis in cancer cells ...

InChl Key
OWUREPXBPJFMOK-CIRFPNLUSA-N
Canonical SMILES
CCC(C)C1C(=O)OC(C(=O)N(C(C(=O)OC(C(=O)N(C(C(=O)OC(C(=O)N1C)C(C)C)C(C)C)C)C(C)C)C(C)CC)C)C(C)C
Isomeric SMILES
CC[C@H](C)[C@H]1C(=O)O[C@@H](C(=O)N([C@H](C(=O)O[C@@H](C(=O)N([C@H](C(=O)O[C@@H](C(=O)N1C)C(C)C)[C@@H](C)CC)C)C(C)C)C(C)C)C)C(C)C
Compound Classification

Chemical Classification:

Cyclodepsipeptide

 

Storage, handling
Store in a freezer upon arrival, at -10°C to -25°C
Open carefully.
Use the original container to store the product.
Keep the lid tightly closed.
Avoid exposing to strong direct light.
Other vendors may recommend higher temperatures for storage.
Retest time
3 Years
Disclaimer
For Research use only
Not for Human or Drug use
Not extracted from humans or animals
Refer to MSDS for further safety and handling instructions
Ingredient type
Fermentek product
Available since

Altenuene

Altenuene
Molecular Formula
C15H16O6
M.W.
292.28
CAS number
29752-43-0
MSDS
Source
Alternaria sp.
Fermentek product Code
ALT-001
Brand/grade
For research
Appearance
White to off white powder
Purity by HPLC
≥98% ; refer to CoA for more data
Purity By TLC
≥98% ; refer to CoA for more data
Solubility test
Clear colorless solution at 5mg/ml of Acetone or Methanol
Names and identifiers

Synonyms:

Chemical names:

Systematic name: 6H-Dibenzo(b,d)pyran-6-one, 2,3,4,4a-tetrahydro-2,3,7-trihydroxy-9-methoxy-4a-methyl-, (2-alpha,3-beta,4a-beta)-(+-)-

IUPAC: (2S,3S,4aS)-2,3,7-Trihydroxy-9-methoxy-4a-methyl-2,3,4,4a-tetrahydro-6H-benzo[c]chromen-6-one                              

RTECS#  HP8758000

EU number
814-111-4
Description

Mycotoxin from Alternaria moulds.

InChl Key
MMHTXEATDNFMMY-WBIUFABUSA-N
Canonical SMILES
CC12CC(C(C=C1C3=CC(=CC(=C3C(=O)O2)O)OC)O)O
Isomeric SMILES
C[C@]12C[C@@H]([C@H](C=C1C3=CC(=CC(=C3C(=O)O2)O)OC)O)O
Storage, handling
Store in a freezer upon arrival, at -10°C to -25°C
Protect from moisture
Open carefully.
Use the original container to store the product.
Keep the lid tightly closed.
Avoid exposing to strong direct light.
Store under argon.
Other vendors may recommend higher temperatures for storage.
Retest time
3 Years
Disclaimer
For Research use only
Not for Human or Drug use
Not extracted from humans or animals
Refer to MSDS for further safety and handling instructions
Ingredient type
Fermentek product
Available since
Title
Transport information
Value
Not hazardous for transport
Title
Deleted CAS Numbers
Value
916665-00-4; 31273-73-1;
Title
CAS comments
Value
Two distinct compounds: 889101-41-1 (-)(-)Altenuene from alternaria and 29752-43-0
Signal to sort
A

Destruxin B

Destruxin B
Molecular Formula
C30H51N5O7
M.W.
593.76
CAS number
2503-26-6
MSDS
Source
Metarhizium anisopliae
Fermentek product Code
DSB-001
Brand/grade
For research
Appearance
White to off white powder
Purity by HPLC
≥96% ; refer to CoA for more data
Purity By TLC
≥98% ; refer to CoA for more data
Solubility test
Clear colorless solution at 10mg/ml of Dichloromethane; Clear colorless solution at 10mg/ml of DMSO
Names and identifiers

Synonyms:

Chemical names:

IUPAC:

RTECS# HH1500100

EU number
not on EC
Description

natural product

 

 

InChl Key
GNBHVMBELHWUIF-UHFFFAOYSA-N
Canonical SMILES
CCC(C)C1C(=O)N(C(C(=O)N(C(C(=O)NCCC(=O)OC(C(=O)N2CCCC2C(=O)N1)CC(C)C)C)C)C(C)C)C
Compound Classification

chemical:

Natural cyclic depsipeptide 

Storage, handling
Store in a freezer upon arrival, at -10°C to -25°C
Protect from moisture
Open carefully.
Use the original container to store the product.
Keep the lid tightly closed.
Avoid exposing to strong direct light.
Other vendors may recommend higher temperatures for storage.
Retest time
3 Years
Disclaimer
For Research use only
Not for Human or Drug use
Not extracted from humans or animals
Refer to MSDS for further safety and handling instructions
Ingredient type
Fermentek product
Available since

Destruxin A

Molecular Formula
C29H47N5O7
M.W.
577.71
CAS number
6686-70-0
MSDS
Source
Metarhizium anisopliae
Fermentek product Code
DSA-001
Brand/grade
For research
Appearance
White to off white powder
Purity by HPLC
≥96% ; refer to CoA for more data
Purity By TLC
≥98% ; refer to CoA for more data
Solubility test
Clear colorless solution at 10mg/ml of Dichloromethane;
Clear colorless solution at 10mg/ml of DMSO
Names and identifiers

Synonyms:

Chemical names:

IUPAC:  (3S,6S,9S,16R,21aS)-16-Allyl-3-[(2S)-2-butanyl]-6-isopropyl-5,8,9-trimethyldodecahydropyrrolo[1,2-d][1,4,7,10,13,16]oxapentaazacyclononadecine-1,4,7,10,14,17(11H,16H)-hexone 

RTECS# HH1500000

EU number
636-280-1
Description

Destruxins are metabolites of a fungus Metarhizium anisopliae. Chemically, these substances are classified as  cyclic hexa-depsipeptides. They posess insecticidal, anti-viral, and phytotoxic propereties. Recently, there is also growing interest in their toxicity to cancer cells.

InChl Key
XIYSEKITPHTMJT-UHFFFAOYSA-N
Canonical SMILES
CCC(C)C1C(=O)N(C(C(=O)N(C(C(=O)NCCC(=O)OC(C(=O)N2CCCC2C(=O)N1)CC=C)C)C)C(C)C)C
Compound Classification

chemical:

Natural cyclic depsipeptide 

Storage, handling
Store in a freezer upon arrival, at -10°C to -25°C
Protect from moisture
Open carefully.
Use the original container to store the product.
Keep the lid tightly closed.
Avoid exposing to strong direct light.
Other vendors may recommend higher temperatures for storage.
Retest time
3 Years
Disclaimer
For Research use only
Not for Human or Drug use
Not extracted from humans or animals
Refer to MSDS for further safety and handling instructions
Ingredient type
Fermentek product
Available since
Title
Transport information
Value
Not hazardous for transport
Signal to sort
D