Destruxins are metabolites of a fungus Metarhizium anisopliae. Chemically, these substances are classified as cyclic hexa-depsipeptides. They posess insecticidal, anti-viral, and phytotoxic propereties. Recently, there is also growing interest in their toxicity to cancer cells.
chemical:Natural cyclic depsipeptide
1: Pal S, St Leger RJ, Wu LP. Fungal peptide Destruxin A plays a specific role in suppressing the innate immune response in Drosophila melanogaster. J Biol Chem. 2007 Mar 23;282(12):8969-77. Epub 2007 Jan 16. PubMed PMID: 17227774.