Food-safety related products include natural toxins which may (but should NOT) occur in food-stuffs, standartized "injection-ready" solutions of toxins in commonly used solvents and the like.

The standard solutions serve as the quantitatively reliable samples of the toxic materials, obtained from tested samples of food by conventional extraction methods.

Highly purified solid toxins serve as starting materials for preparation of antibodies, which may be a part of bioassays etc.

Fumonisin B1

Fumonisin B1
Molecular Formula
C34H59NO15
M.W.
721.80
CAS number
116355-83-0
MSDS
Source
Fusarium moniliforme
Fermentek product Code
FB1-001
Brand/grade
For research
Appearance
White to slight yellow powder
Purity by HPLC
≥98% ; refer to CoA for more data
Purity By TLC
≥98% ; refer to CoA for more data
Solubility test
Clear colorless solution at 5 mg/ml Methanol
Names and identifiers

Synonyms:              Macrofusine

Systematic name:  1,2,3-Propanetricarboxylic acid, 1,1'-(1-(12-amino-4,9,11-trihydroxy-2-methyltridecyl)-2-(1-methylpentyl)-1,2-ethanediyl) ester

RTECS : TZ8350000

EU number
621-436-3
Description

A carcinogenic mycotoxin.

An inhibitor of sphingosine biosynthesis

InChl Key
UVBUBMSSQKOIBE-ZWKVXHQASA-N
Canonical SMILES
CCCCC(C)C(C(CC(C)CC(CCCCC(CC(C(C)N)O)O)O)OC(=O)CC(CC(=O)O)C(=O)O)OC(=O)CC(CC(=O)O)C(=O)O
Isomeric SMILES
CCCC[C@H](C)[C@H]([C@@H](C[C@H](C)C[C@H](CCCC[C@H](C[C@@H]([C@H](C)N)O)O)O)OC(=O)C[C@H](CC(=O)O)C(=O)O)OC(=O)C[C@H](CC(=O)O)C(=O)O
Solubility ( literature )

Slightly soluble in water. Soluble in Acetonitril. Insoluble in Chloroform, Petrol Ether, Hexane.

Compound Classification

Chemical classification

  • Isoflavonoid
  • Phytoestrogen

Biological activities

  • Sphingosine acyl-transterase inhibitor
  • Ceramide-synthase inhibitor
  • Teratogen
  • Carcinogen
Storage, handling
Store in a freezer upon arrival, at -10°C to -25°C
Use the original container to store the product.
Keep the lid tightly closed.
Avoid exposing to strong direct light.
Other vendors may recommend higher temperatures for storage.
Disclaimer
For Research use only
Not for Human or Drug use
Not extracted from humans or animals
Ingredient type
Fermentek product
Title
Transport information
Value
Not hazardous for transport
Title
TSE
Value
P
Signal to sort
F

Fumagillin

Fumagillin
Molecular Formula
C26H34O7
M.W.
458.54
CAS number
23110-15-8
MSDS
Source
Aspergillus fumigatus
Fermentek product Code
FUG-001
Appearance
Off-white to slight yellow powder
Purity by HPLC
≥95% ; refer to CoA for more data
Purity By TLC
≥98% ; refer to CoA for more data
Melting point
190°C-202°C
Solubility test
Clear colorless solution at 30mg/ml DMSO,
Clear colorless solution at 1mg/ml Ethanol
Names and identifiers

Synonyms:

  • Fumidil B,
  • Amebacilin,

IUPAC Name   (2E,4E,6E,8E)-10-({(3R,4S,5S,6R)-5-Methoxy-4-[(2R,3R)-2-methyl-3-(3-methyl-2-buten-1-yl)-2-oxiranyl]-1-oxaspiro[2.5]oct-6-yl}oxy)-10-oxo-2,4,6,8-decatetraenoic acid 

RTECS :             HE1750000

EU number
245-433-8
Description

Antiamoebic. Inhibitor of angiogenesis.

Reproduction effector

InChl Key
NGGMYCMLYOUNGM-CSDLUJIJSA-N
Canonical SMILES
CC(=CCC1C(O1)(C)C2C(C(CCC23CO3)OC(=O)C=CC=CC=CC=CC(=O)O)OC)C
Isomeric SMILES
CC(=CC[C@@H]1[C@@](O1)(C)[C@H]2[C@@H]([C@@H](CC[C@]23CO3)OC(=O)/C=C/C=C/C=C/C=C/C(=O)O)OC)C
Solubility ( literature )

DMSO, Methanol. alkaline aqueous solutions

Compound Classification

Chemical classification:

Fatty acid antibiotic.

Classification by bio-activity

Antiprotozoal

Storage, handling
Store in a freezer upon arrival, at -10°C to -25°C
Protect from moisture
Avoid exposing to strong direct light.
Store under argon.
Other vendors may recommend higher temperatures for storage.
Disclaimer
For Research use only
Not for Human or Drug use
Not extracted from humans or animals
Refer to MSDS for further safety and handling instructions
Semi-Synthetic
Ingredient type
Fermentek product
Transport safety: Not Dangerous Goods; Not Regulated
Available since
Title
Transport information
Value
Not hazardous for transport
Signal to sort
F

Dihydrocytochalasin B

Dihydrocytochalasin B
Molecular Formula
C29H39NO5
M.W.
481.60
CAS number
39156-67-7
MSDS
Source
Semisynthetic
Fermentek product Code
DHB-001
Brand/grade
For research
Appearance
White powder
Purity by HPLC
≥95% ; refer to CoA for more data
Purity By TLC
≥98% ; refer to CoA for more data
Melting point
195°C-205°C
Solubility test
Clear colorless solution at 10mg/ml Methanol
Names and identifiers

Synonyms:  

  • 21,22-Dihydrochalasin B
  • 21,22-Dihydrocytochalasin B
  • 21,22-Dihydrophomin

 

Systematic Name: 7(S),20(R)-Dihydroxy-16(R)-methyl-10-phenyl-24-oxa(14)cytochalasa-6(12),13(E)-diene-1,23-dione

EU number
254-324-4
Description

Dihydrocytochalasin B is chemically derived from Cytochalasin B  obtained natural from Drechslera dematoidea fungus.

InChl Key
WIULKAASLBZREV-RXPQEOCGSA-N
Canonical SMILES
CC1CCCC(CCC(=O)OC23C(C=CC1)C(C(=C)C(C2C(NC3=O)CC4=CC=CC=C4)C)O)O
Isomeric SMILES
C[C@@H]1CCC[C@H](CCC(=O)O[C@]23[C@@H](/C=C/C1)[C@@H](C(=C)[C@H]([C@H]2[C@@H](NC3=O)CC4=CC=CC=C4)C)O)O
Solubility ( literature )

Acetone, DMSO, 100% Ethanol, Methanol

Compound Classification
  • Macrolide indol mycotoxin
  • Cytochalasin
  • Actin inhibitor
Storage, handling
Deep frozen (-15 oC to - 20 oC)
Applications

Cytochalasins are used as tools in cytological research, and in in the field of actin polymerisation.

Cytokinesis inhibitor. Inducer of changes in cell morphology and motility. It disrupts actin structure and inhibits ability of serum growth factors to stimulate DNA synthesis in vitro. Does not inhibit sugar uptake. Active calcium transport inhibitor. Active in vivo.

 

Ingredient type
Fermentek product
Available since
Title
sig
Value
250225
Title
TSE
Value
S
Title
Transport information
Value
Pg III
Title
EU
Value
254-324-4; On REACH List of Pre-Registered Substances, March 2009 Registration Date: 31-MAY-2013
Title
CAS deleted numbers
Value
74409-92-0 ;
Title
Other sites info
Value
Most sites give wrong RTECS number RO0205000 belonging to Phomin
Signal to sort
D

Diacetoxyscirpenol (DAS)

Molecular Formula
C19H26O7
M.W.
366.41
CAS number
2270-40-8
Source
Fusarium sp
Fermentek product Code
DAS-001
Appearance
White powder
Purity by HPLC
≥98% ; refer to CoA for more data
Purity By TLC
≥98% ; refer to CoA for more data
Melting point
160°C-165°C
Solubility test
Clear colorless solution at 10mg/ml Methanol ; Clear colorless solution at 10mg/ml dichloromethane
Names and identifiers

Synonyms

  • Anguidine,
  • DAS
  • Diacetoxyscirpenol

RTECS YD0112000

 

EU number
218-873-3
Description

Diacetoxyscirpenol (DAS) also known as Anguidine,  is a mycotoxin belonging to 12,13-epoxytrichothecene group, produced by several Fusarium strains together with some other toxins such as T2 and HT2 toxins.

 DAS inhibits initiation of protein synthesis, causing the death of intensively replicating cells. By the virtue of this effect, DAS possesses teratogenic and anti proliferatory properties. Consequently,  DAS attracts interest as a potential cancer- drug.

 

 

InChl Key
AUGQEEXBDZWUJY-ZLJUKNTDSA-N
Canonical SMILES
CC1=CC2C(CC1)(C3(C(C(C(C34CO4)O2)O)OC(=O)C)C)COC(=O)C
Isomeric SMILES
CC1=C[C@@H]2[C@](CC1)([C@]3([C@@H]([C@H]([C@H]([C@]34CO4)O2)O)OC(=O)C)C)COC(=O)C
Solubility ( literature )

Soluble in moderately polar solvents, such as chloroform, diethyl ether, ethyl acetate, and acetone

Compound Classification
  • trichothecene mycotoxin
  • Apoptosis inducer
Storage, handling
Store in a freezer upon arrival, at -10°C to -25°C
Avoid exposing to strong direct light.
Other vendors may recommend higher temperatures for storage.
Expiration time
1Y
Retest time
1Y
Applications

Diacetoxyscirpenol (Anguidine) and its derivates possess anticancer properties. Diacetoxyscirpenol (Anguidine) inhibits initiation of protein synthesis, resulting in the death of rapidly proliferating cells. Diacetoxyscirpenol (Anguidine) also has been shown to both potentiate and protect against the cytotoxic effects of other drugs. There were 14 clinical trials reported, all in the area of colorectal tumors and leukemia. No records found after 1985. Apoptosis inducement.

Disclaimer
For Research use only
Not for Human or Drug use
Not extracted from humans or animals
Refer to MSDS for further safety and handling instructions
Semi-Synthetic
Ingredient type
Fermentek product
Available since
Title
Deleted CAS Numbers
Value
11011-10-2 ; 22135-66-6 ; 25662-95-7 ; 28776-47-8 ; 109547-11-7 ; 145427-91-4 ; 852223-87-1 ;
Title
Transport information
Value
Pg II
Signal to sort
D

15-acetyl Deoxynivalenol

15-acetyl Deoxynivalenol
Molecular Formula
C17H22O7
M.W.
338.35
CAS number
88337-96-6
Source
Semisynthetic
Fermentek product Code
15D-001
Brand/grade
For research
Appearance
White powder
Purity by HPLC
≥98% ; refer to CoA for more data
Purity By TLC
≥98% ; refer to CoA for more data
Melting point
130°C-140°C
Solubility test
Clear colorless solution at 10mg/ml Methanol or Ethyl acetate
Names and identifiers

Synonyms:

  • 15-acetyl don;
  • 15-acetyldeoxynivalenol;
  • 15-O-Acetyl-4-deoxynivalenol;

RTECS:  YD0155000

 

EU number
621-572-3
Description

Natural, Type B trichothecene mycotoxin

InChl Key
IDGRYIRJIFKTAN-HTJQZXIKSA-N
Canonical SMILES
CC1=CC2C(C(C1=O)O)(C3(CC(C(C34CO4)O2)O)C)COC(=O)C
Isomeric SMILES
CC1=C[C@@H]2[C@]([C@@H](C1=O)O)([C@]3(C[C@H]([C@H]([C@@]34CO4)O2)O)C)COC(=O)C
Solubility ( literature )

15-acetyl Deoxynivalenol is soluble in common polar organic solvents as acetonitrile, methanol and ethyl acetate, only slightly soluble in water. Trichothecenes with acetoxy-groups are unstable in methanol, even when stored in a freezer [H. Pettersson, EU-Commission Progress Report SMT4-CT96-2047, 1-24, (1998), "Intercomparison of trichothecene analysis and feasibility to produce certified calibrants and reference material"] Acetonitrile is recommended as solvent for 15-acetyl Deoxynivalenol as it has no significant UV absorbance below 220 nm.

Compound Classification

Trichothecene mycotoxin

Storage, handling
Store in a freezer upon arrival, at -10°C to -25°C
Ingredient type
Fermentek product
Available since
Title
Transport information
Value
Pg II
Title
RTECS
Value
YD0155000
Signal to sort
D

3-acetyl Deoxynivalenol

3-acetyl Deoxynivalenol
Molecular Formula
C17H22O7
M.W.
338.35
CAS number
50722-38-8
Source
Fusarium graminearum
Fermentek product Code
3AD-001
Brand/grade
For research
Appearance
White powder
Purity by HPLC
≥98% ; refer to CoA for more data
Purity By TLC
≥98% ; refer to CoA for more data
Melting point
184°C-189°C
Solubility test
Clear colorless solution at 10mg/ml Methanol or Ethyl acetate
Names and identifiers

 

  • 3ADON
  • 3α-Acetylvomitoxin
  • 3-Acetyl DON
  • 3-Acetyldeoxynivalenol
  • Dehydronivalenol monoacetate
  • Deoxynivalenol monoacetate

RTECS: YD0167000

EU number
621-771-5
Description

Natural Type B trichothecene mycotoxin

InChl Key
ADFIQZBYNGPCGY-HTJQZXIKSA-N
Canonical SMILES
CC1=CC2C(C(C1=O)O)(C3(CC(C(C34CO4)O2)OC(=O)C)C)CO
Isomeric SMILES
CC1=C[C@@H]2[C@]([C@@H](C1=O)O)([C@]3(C[C@H]([C@H]([C@@]34CO4)O2)OC(=O)C)C)CO
Solubility ( literature )

3-acetyl Deoxynivalenol is soluble in common polar organic solvents as acetonitrile, methanol and ethyl acetate, only slightly soluble in water.

Compound Classification

Trichothecene mycotoxin

Storage, handling
Store in a freezer upon arrival, at -10°C to -25°C
Open carefully.
Avoid exposing to strong direct light.
Other vendors may recommend higher temperatures for storage.
Disclaimer
For Research use only
Not for Human or Drug use
Not extracted from humans or animals
Refer to MSDS for further safety and handling instructions
Semi-Synthetic
Ingredient type
Fermentek product
Available since
Title
Deleted CAS Numbers:
Value
115825-62-2; 233593-19-6
Title
Transport information
Value
Pg II
Signal to sort
D

Deoxynivalenol

Deoxynivalenol (DON)
Molecular Formula
C15H20O6
M.W.
296.30
CAS number
51481-10-8
MSDS
Source
Semisynthetic
Fermentek product Code
DON-001
Brand/grade
For research
Appearance
White crystalline solid.
Purity by HPLC
≥98% ; refer to CoA for more data
Purity By TLC
≥98% ; refer to CoA for more data
Melting point
150°C-155°C
Solubility test
Clear colorless solution at 10mg/ml Methanol or Ethyl acetate

Names and identifiers
  • Rd toxin
  • Vomitoxin
  • Deoxynivalenol
  • 4-Deoxynivalenol
  • Dehydronivalenol
  • 4-Desoxynivalenol

RTECS YD0167000

EU number
610-668-0
Description

Deoxynivalenol (DON , Vomitoxin) is a type B trichothecene. It occurs in grains such as wheat, barley, oats, rye, and maize, rice, sorghum. Deoxynivalenol (DON ) is produced by numerous strains of Fusarium and some other fungi. Deoxynivalenol (DON ) poisonings occur both in humans and farm animals. Deoxynivalenol (DON ) is highly toxic, producing a wide range of immunological disturbances and is particularly noted for inducing feed refusal and emesis in pigs, hence the alternative name vomitoxin Deoxynivalenol (DON ) usually co-occurs with other Fusarium toxins, such as Zearalenone, Nivalenol and its derivates, as well as the group of fumonisins.

InChl Key
LINOMUASTDIRTM-QGRHZQQGSA-N
Canonical SMILES
CC1=CC2C(C(C1=O)O)(C3(CC(C(C34CO4)O2)O)C)CO
Isomeric SMILES
CC1=C[C@@H]2[C@]([C@@H](C1=O)O)([C@]3(C[C@H]([C@H]([C@@]34CO4)O2)O)C)CO
Solubility ( literature )

Deoxynivalenol (DON ) is soluble in common polar organic solvents as acetonitrile, methanol and ethyl acetate, slightly soluble in water.

Compound Classification

trichothecene type B mycotoxin

Storage, handling
Store in a freezer upon arrival, at -10°C to -25°C
Protect from moisture
Other vendors may recommend higher temperatures for storage.
Applications

The main toxic effect of Deoxynivalenol (DON ) is inhibition of protein synthesis via binding to the ribosome.In agricultural R&D, DON is widely used to select crops strains with increased resistance against Fusarium.

Disclaimer
For Research use only
Not for Human or Drug use
Not extracted from humans or animals
Refer to MSDS for further safety and handling instructions
Semi-Synthetic
Ingredient type
Fermentek product
Available since
Title
Deleted CAS Numbers
Value
50722-37-7 ; 115825-61-1 ; 1394244-12-2
Signal to sort
D

Cytochalasin E

Cytochalasin E
Molecular Formula
C28H33NO7
M.W.
495.56
CAS number
36011-19-5
MSDS
Source
Aspergillus clavatus
Fermentek product Code
CYE-001
Brand/grade
For research
Appearance
White powder
Purity by HPLC
≥98% ; refer to CoA for more data
Purity By TLC
≥98% ; refer to CoA for more data
Melting point
205°C-220°C
Solubility test
Clear colorless solution at 50mg/ml DMSO
Names and identifiers

 

HSDB 3548

RTECS HA5360000

EU number
252-835-7
Description

Inhibitor of actin polymerization in blood platelets. It does not inhibit glucose transport.

InChl Key
LAJXCUNOQSHRJO-ZYGJITOWSA-N
Canonical SMILES
CC1CC=CC2C3C(O3)(C(C4C2(C(=O)NC4CC5=CC=CC=C5)OC(=O)OC=CC(C1=O)(C)O)C)C
Isomeric SMILES
C[C@H]1C/C=C/[C@H]2[C@H]3[C@](O3)([C@H]([C@@H]4[C@]2(C(=O)N[C@H]4CC5=CC=CC=C5)OC(=O)O/C=C/[C@@](C1=O)(C)O)C)C
Solubility ( literature )

DMSO, ethyl acetate, ethanol, dichloromethane

Compound Classification

Macrolide indol mycotoxin

Cytochalasin

Actin polymerization inhibitor

Antiangiogenic

 

Storage, handling
Store in a freezer upon arrival, at -10°C to -25°C
Ingredient type
Fermentek product
Available since
Title
since
Value
1999
Signal to sort
C

Cytochalasin D

Cytochalasin D
Molecular Formula
C30H37NO6
M.W.
507.62
CAS number
22144-77-0
MSDS
Source
Zygosporium mansonii
Fermentek product Code
CYD-001
Brand/grade
For research
Appearance
White powder
Purity by HPLC
≥97% ; refer to CoA for more data
Purity By TLC
≥98% ; refer to CoA for more data
Melting point
230°C-245°C
Solubility test
Clear colorless solution at 25mg/ml DMSO, Clear colorless solution at 5mg/ml Ethanol
Names and identifiers

Synonyms: Zygosporin A

Chemical Name: (7S,13E,16S,18R,19E,21R)-21-(Acetyloxy)- 7,18-dihydroxy-16,18-dimethyl-10-phenyl[11]cytochalasa-6(12),13,19-triene-1,17-dione

EU number
244-804-1
Description

Cytochalasin D is a cell permeable mycotoxin, which causes both the association and dissociation of actin subunits. Cytochalasin D disrupts actin filaments and inhibits actin polymerization.

InChl Key
SDZRWUKZFQQKKV-JHADDHBZSA-N
Canonical SMILES
CC1CC=CC2C(C(=C)C(C3C2(C(C=CC(C1=O)(C)O)OC(=O)C)C(=O)NC3CC4=CC=CC=C4)C)O
Isomeric SMILES
C[C@H]1C/C=C/[C@H]2[C@@H](C(=C)[C@H]([C@@H]3[C@@]2([C@@H](/C=C/[C@@](C1=O)(C)O)OC(=O)C)C(=O)N[C@H]3CC4=CC=CC=C4)C)O
Solubility ( literature )

DMSO, Ethanol, Methanol

Compound Classification
  • Macrolide indol mycotoxin
  • Cytochalasin
  • Actin inhibitor
Storage, handling
Store in a freezer upon arrival, at -10°C to -25°C
Protect from moisture
Open carefully.
Use the original container to store the product.
Avoid exposing to strong direct light.
Store under argon.
Other vendors may recommend higher temperatures for storage.
Applications

Cytochalasins are used as tools in cytological research, and in the field of actin polymerization. Cytochalasin D is 10 times more effective than cytochalasin B and does not inhibit glucose transport across cell membranes.

Disclaimer
For Research use only
Not for Human or Drug use
Not extracted from humans or animals
Refer to MSDS for further safety and handling instructions
Ingredient type
Fermentek product
Available since
Title
Deleted CAS Numbers
Value
11032-97-6 ; 25852-72-6 ; 28455-04-1 ; 69401-32-7
Title
TSE
Value
V
Title
sig
Value
250255
Signal to sort
C

Cytochalasin C

Cytochalasin C
Molecular Formula
C30H37NO6
M.W.
507.62
CAS number
22144-76-9
MSDS
Source
Metarhizium anisopliae
Fermentek product Code
CYC-001
Brand/grade
For research
Appearance
White powder
Purity by HPLC
≥98% ; refer to CoA for more data
Purity By TLC
≥98% ; refer to CoA for more data
Melting point
265°C-280°C
Solubility test
Clear colorless solution at 5mg/ml Dichloromethane
Names and identifiers

RTECS: HA5300500

EU number
244-803-6
Description

A fungal metabolite that acts as a potent inhibitor of actin filament and contractile microfilaments.

InChl Key
NAIODHJWOHMDJX-BBXOWAOSSA-N
Canonical SMILES
CC1CC=CC2C(C(=C(C3C2(C(C=CC(C1=O)(C)O)OC(=O)C)C(=O)NC3CC4=CC=CC=C4)C)C)O
Isomeric SMILES
CC1C/C=C/C2C(C(=C(C3C2(C(/C=C/C(C1=O)(C)O)OC(=O)C)C(=O)NC3CC4=CC=CC=C4)C)C)O
Solubility ( literature )

Dichloromethane , Ethyl acetate

Compound Classification

Macrolide indol mycotoxinCytochalasinActin inhibitor

Storage, handling
-20°C. Protect from light.
Applications

Cytochalasins are used as tools in cytological research, and in the field of actin polymerisation

Disclaimer
For Research use only
Not for Human or Drug use
Not extracted from humans or animals
Refer to MSDS for further safety and handling instructions
Ingredient type
Fermentek product
Available since