Emodin

Emodin
Molecular Formula
C15H10O5
M.W.
270.24
CAS number
518-82-1
MSDS
Fermentek product Code
EMO-001
Brand/grade
For research
Appearance
Orange Powder
Purity by HPLC
≥98% ; refer to CoA for more data
Purity By TLC
≥98% ; refer to CoA for more data
Melting point
255°C-265°C
Solubility test
Clear yellow to red solution at 50mg/ml of DMSO;
Clear yellow to red solution at 10mg/ml of Ethanol (may need a little warming)
Names and identifiers

Synonyms

  • Archin
  • Emodol
  • Frangula emodin
  • Frangulic acid
  • Rheum emodin

 Chemical names    Emodin

RTECS                    CB7920600

EU number
208-258-8
Chemical name
Emodin
Description

 Emodin is an anthraquinone class compound. It is sourced from a plant Rheum palmatum. It exhibits antibacterial, anti-neoplastic, anti-inflammatory and anti-angiogenesis properties. 

InChl Key
RHMXXJGYXNZAPX-UHFFFAOYSA-N
Canonical SMILES
C1=CC2=C(C(=C1)O)C(=O)C3=C(C2=O)C=C(C=C3O)O
Solubility ( literature )

Water Solubility <0.1 g/100 mL at 19ºC ; Practically insoluble in water; soluble in alcohol, aqueous alkali hydroxide solutions (cherry red color), (src: Merck index)

Compound Classification

Emodin has been investigated for the treatment of Polycystic Kidney.

Storage, handling
Store in a freezer upon arrival, at -10°C to -25°C
Open carefully.
Use the original container to store the product.
Keep the lid tightly closed.
Avoid exposing to strong direct light.
Other vendors may recommend higher temperatures for storage.
Disclaimer
For Research use only
Not for Human or Drug use
Not extracted from humans or animals
Refer to MSDS for further safety and handling instructions
Ingredient type
Fermentek product
Shipped at ambient temperature
Shipped in PP / PE bottle.
Available since
Title
phys appearance
Value
Emodin appears as orange needles or powder.
Title
CN EU 29146980
Value
Ketones and quinones; Quinones; Other; Other
Title
Usage:
Value
Only for research in the field of cancer
Title
Usage:
Value
Emodin has been investigated for the treatment of Polycystic Kidney
Signal to sort
E

Triacsin C

Triacsin C
Molecular Formula
C11H17N3O
M.W.
207.27
CAS number
76896-80-5
MSDS
Source
Streptomyces aureofaciens
Fermentek product Code
TRC-001
Brand/grade
For research
Appearance
Off-white to Dark yellow powder
Purity by HPLC
≥90% ; refer to CoA for more data
Purity By TLC
≥95% ; refer to CoA for more data
Solubility test
Clear yellowish to yellow solution at 5mg/ml of Methanol or DMSO
Names and identifiers

Synonyms

  • 2E, 4E, 7E-Undecatriene-1-triazene
  • 1-hydroxy-3-(2',4',7'-undecatrienylidine)triazene

 

EU number
616-408-2
Chemical name
2,4,7-Undecatrienal, nitrosohydrazone, (2E,4E,7E)-
Description

Triacsin C, an analog of polyunsaturated fatty acid. A potent vasodilator.

InChl Key
NKTGCVUIESDXPU-YLEPRARLSA-N
Canonical SMILES
CCCC=CCC=CC=CC=NNN=O
Isomeric SMILES
CCC/C=C/C/C=C/C=C/C=N/NN=O
Solubility ( literature )

Soluble to 25 mM in DMSO (lit)

Compound Classification

Chemical classification:

  • Triazene class compound
  • Polyunsaturated fatty acid analog.

Classification by bioactivities:

  • Arachidonoyl-CoA synthetase inhibitor
  • Inhibits Synthesis of triacylglycerol and phospholipid
  • Apoptosis inhibitor
  • Vasodilator
Storage, handling
Store in a freezer upon arrival, at -10°C to -25°C
Protect from moisture
Protect from light !
Avoid exposing to strong direct light.
Store under argon.
Other vendors may recommend higher temperatures for storage.
Attention: this compound may deteriorate quickly if stored improperly
Retest time
1Y
Applications

Selectively inhibits arachidonoyl-CoA synthetase in intact cells. Inhibits the nonspecific acyl-CoA synthetase in cell sonicates. Inhibits neutrophil functions. Inhibits lipid synthesis and cell proliferation in Raji lymphoma cells. Induces apoptosis in cancer cell lines and inhibits human lung cancer cell xenograft tumor growth in mice.

Disclaimer
For Research use only
Not for Human or Drug use
Not extracted from humans or animals
Refer to MSDS for further safety and handling instructions
Ingredient type
Fermentek product
Available since
Title
Inhibitor of:
Value
Selective inhibitor of acyl-CoA synthetase
Title
Transport information
Value
Not hazardous for transport
Title
Specifications updated 24-October 2017
Value
Purity ≥90% by HPLC
Signal to sort
T