Concanamycin A (Folimycin)
Molecular Formula
C46H75NO14
M.W.
866.09
CAS number
80890-47-7
MSDS
Source
Streptomyces sp.
Fermentek product Code
CON-001
Brand/grade
For research
Appearance
White to off white powder
Purity by HPLC
≥97% ; refer to CoA for more data
Purity By TLC
≥98% ; refer to CoA for more data
Solubility test
Clear colorless solution at 10mg/ml of Methanol
Names and identifiers

Synonyms:

  • Concamycin A
  • Folimycin
  • Concanamycin

Comment: Many other suppliers, as well as PUBCHEM, CHEMSPIDER and publications, consider Folimycin and Concanamycin A to be synonyms, while SCIFINDER considers these compounds to be different.

IUPAC: 

3-O-(4-O-Carbamoyl-2,6-dideoxy-β-D-arabino-hexopyranosyl)-2,4-dideoxy-1-C-{4-[(4E,6E,14E,16Z)-11-ethyl-10,12-dihydroxy-3,17-dimethoxy-7,9,13,15-tetramethyl-18-oxooxacyclooctadeca-4,6,14,16-tetraen- 2-yl]-3-hydroxy-2-pentanyl}-4-methyl-5-[(1E)-1-propen-1-yl]-β-D-threo-pentopyranose

RTECS# CB9732000

EU number
620-709-4
Chemical name
Concanamycin A
Description

Macrolide type antibiotic, ATPase inhibitor, having antiproliferative, antifungal and antimalarial effects.

InChl Key
DJZCTUVALDDONK-HQMSUKCRSA-N
Canonical SMILES
CCC1C(C(CC(=CC=CC(C(OC(=O)C(=CC(=CC(C1O)C)C)OC)C(C)C(C(C)C2(CC(C(C(O2)C=CC)C)OC3CC(C(C(O3)C)OC(=O)N)O)O)O)OC)C)C)O
Isomeric SMILES
CC[C@H]1[C@H]([C@@H](C/C(=C/C=C/[C@@H]([C@H](OC(=O)/C(=C/C(=C/[C@H]([C@H]1O)C)/C)/OC)[C@@H](C)[C@H]([C@H](C)[C@]2(C[C@H]([C@@H]([C@H](O2)/C=C/C)C)O[C@H]3C[C@H]([C@@H]([C@H](O3)C)OC(=O)N)O)O)O)OC)/C)C)O
Solubility ( literature )

Concanamycin A is reported to be soluble in chloroform, methanol, ethanol, acetone, ethyl acetate, and DMSO. Concanamycin A is not soluble in water.

Storage, handling
Store in a freezer upon arrival, at -10°C to -25°C
Store under argon
Protect from moisture
Protect from light
Use the original container to store the product.
Keep the lid tightly closed.
Disclaimer
For Research use only
Not for Human or Drug use
Not extracted from humans or animals
Refer to MSDS for further safety and handling instructions
Warnings

NotGMO

Product natural

Ingredient type
Fermentek product
Available since
Title
Transport information
Value
Pg II
Title
CN code
Value
--
Title
Depreciated CAS Registry Numbers
Value
66771-59-3
Signal to sort
C