Concanamycin A (Folimycin)

Molecular Formula:

C46H75NO14

CAS number:

80890-47-7

EU number:

620-709-4

Fermentek product code:

Source:

Streptomyces sp.

Brand/grade:

For research

Specifications

Appearance:

White crystals

Purity by HPLC:

≥97% ; refer to CoA for more data

Purity By TLC:

≥98% ; refer to CoA for more data

Solubility test:

Clear colorless solution at 10mg/ml of Methanol

Chemical identification

Names and identifiers:

Synonyms:

Concamycin A
Folimycin
Concanamycin

Comment: Many other suppliers, as well as PUBCHEM, CHEMSPIDER and publications, consider Folimycin and Concanamycin A to be synonyms, while SCIFINDER considers these compounds to be different.

IUPAC:

3-O-(4-O-Carbamoyl-2,6-dideoxy-β-D-arabino-hexopyranosyl)-2,4-dideoxy-1-C-{4-[(4E,6E,14E,16Z)-11-ethyl-10,12-dihydroxy-3,17-dimethoxy-7,9,13,15-tetramethyl-18-oxooxacyclooctadeca-4,6,14,16-tetraen- 2-yl]-3-hydroxy-2-pentanyl}-4-methyl-5-[(1E)-1-propen-1-yl]-β-D-threo-pentopyranose

RTECS# CB9732000

Chemical name:

Concanamycin A

Description:

Macrolide type antibiotic, ATPase inhibitor, having antiproliferative, antifungal and antimalarial effects.

Molecular weight:

866.09

InChl Key:

DJZCTUVALDDONK-HQMSUKCRSA-N

Canonical SMILES:

CCC1C(C(CC(=CC=CC(C(OC(=O)C(=CC(=CC(C1O)C)C)OC)C(C)C(C(C)C2(CC(C(C(O2)C=CC)C)OC3CC(C(C(O3)C)OC(=O)N)O)O)O)OC)C)C)O

Isomeric SMILES:

CC[[email protected]]1[[email protected]]([[email protected]@H](C/C(=C/C=C/[[email protected]@H]([[email protected]](OC(=O)/C(=C/C(=C/[[email protected]]([[email protected]]1O)C)/C)/OC)[[email protected]@H](C)[[email protected]]([[email protected]](C)[[email protected]]2(C[[email protected]]([[email protected]@H]([[email protected]](O2)/C=C/C)C)O[[email protected]]3C[[email protected]]([[email protected]@H]([[email protected]](O3)C)OC(=O)N)O)O)O)OC)/C)C)O

Further Information

Solubility ( literature ):

Concanamycin A is reported to be soluble in chloroform, methanol, ethanol, acetone, ethyl acetate, and DMSO.Concanamycin A is not soluble in water.

Storage, handling:

Store in a freezer upon arrival, at -10°C to -25°C

Hygroscopic substance.

Protect from moisture

Protect from light !

Open carefully.

Use the original container to store the product.

Keep the lid tightly closed.

Avoid exposing to strong direct light.

Other vendors may recommend higher temperatures for storage.

Reportedly, OK to freeze; Frozen stock solutions in DMSO are stable 1 year

Disclaimer:

For Research use only

Not for Human or Drug use

Not extracted from humans or animals

Refer to MSDS for further safety and handling instructions

Warnings:

NotGMO

NotGMO.jpg

Composition

Ingredient type:

Fermentek product

Special Info

Available since:

2017

Other Fields

Title:

Transport information

Value:

Pg II

Title:

CN code

Value:

Title:

Depreciated CAS Registry Numbers

Value:

66771-59-3

Concanamycin A (Folimycin)

Specifications

Chemical identification

Further Information

NotGMO

NotGMO.jpg

Composition

Special Info

Other Fields

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Bafilomycin-B1--88899-56-3.png

Concanamycin-A-80890-47-7.png