Mycotoxins are defined as naturally occurring substances produced by filamentous fungi (moulds) that arouse toxic response when introduced in low amounts to animals through a natural pathway. These fungi are referred to as “toxigenic” fungi. They grow naturally as a form of contaminants on some food crops, majorly cereals, nuts and fruit. Conventionally, toxigenic fungi which contaminate crops have been classified into two groups: “field” and “storage” fungi. Field fungi (such as Cladosporium, Fusarium and Alternaria spp.) get to plants during the developmental stage of the plant; while storage fungi (e.g., Aspergillus and Penicillium spp.) proliferate during the storage period.

Mycotoxins, which are low weight secondary metabolites, produce harmful substances called Mycotoxicoses in animals which invariably impact public health. The toxicity effects of Mycotoxins could be acute or chronic, or both. The most toxic of these, is Aflatoxins. Aflatoxins B1, B2, G1 and G2 are a critical concern. A low-level exposure to Aflatoxin for a long term has been associated with different liver diseases such as cancer, jaundice, cirrhosis and hepatis. Also, they are genotoxic (DNA-damaging) carcinogenic and immunosuppressants. Ochratoxin A is another type of mycotoxin that is teratogenic (reproductive), immunosuppressant, and had been proved to have connection with kidney diseases. Other toxigenic fungi are associated with protein synthesis inhibition, genotoxic, and immune dysfunction.

Fermentek is a global leader in the production of high-standard reference material for Mycotoxins for food safety analysis and research. The company offers more than 60 types of Mycotoxins manufactured from various different microorganisms, divided into nine known Mycotoxin families. These products are formulated into a powdered form or standard solutions with high purity characterized by their melting points, TLC & HPLC. 

mycotoxins

Penitrem E

Penitrem E
Molecular Formula
C37H45NO6
M.W.
599.76
CAS number
78213-66-8
Source
Penicillium palitans
Fermentek product Code
PEE
Brand/grade
For research
Purity by HPLC
≥ 99% ; refer to CoA for more data
Solubility test
Clear colorless solution at 10mg/ml of
Dichloromethane
or Methanol
or Ethyl acetate
or Water
Names and identifiers

Synonyms: 

  • Penitrem E
  • 6-Dechloropenitrem A

Chemical names: Penitrem E

IUPAC Name: (1S,2R,5S,6S,8R,9S,10R,12S,15R,16S,25R,27S,28R)-15,16,33,33-tetramethyl-24-methylidene-10-prop-1-en-2-yl-7,11,32-trioxa-18-azadecacyclo[25.4.2.02,16.05,15.06,8.06,12.017,31.019,30.022,29.025,28]tritriaconta-17(31),19(30),20,22(29)-tetraene-5,9,28-triol 

Comptox.EPA.Gov: DTXSID10999456

RTECS# KC9940880

EU number
Not listed as at June 2024
InChl Key
LTCFBVUSILPMGG-BRSLXYMHSA-N
Canonical SMILES
[H][C@]12O[C@@]11[C@]([H])(CC[C@]3(C)[C@@]4(C)C5=C6C7=C(N5)C=CC5=C7[C@@]7(O)[C@]([H])(C[C@]7([H])C(C)(C)O[C@@]6([H])[C@]4([H])CC[C@@]13O)C(=C)C5)O[C@]([H])(C(C)=C)[C@]2([H])O
Isomeric SMILES
CC(=C)[C@@H]1[C@@H]([C@@H]2[C@@]3(O2)[C@@H](O1)CC[C@]4([C@]3(CC[C@@H]5[C@@]4(C6=C7[C@H]5OC([C@H]8C[C@H]9[C@@]8(C1=C(CC9=C)C=CC(=C71)N6)O)(C)C)C)O)C)O
Solubility ( literature )

Tested: Methanol: Clear colorless solution at 10mg/ml
Tested: DMSO: Clear colorless solution at 50mg/ml

Storage, handling
Store in a freezer upon arrival, at -10°C to -25°C
Open carefully.
Use the original container to store the product.
Keep the lid tightly closed.
Avoid exposing to strong direct light.
Other vendors may recommend higher temperatures for storage.
Protect from moisture!
Disclaimer
For Research use only
Not for Human or Drug use
Not extracted from humans or animals
Refer to MSDS for further safety and handling instructions
Ingredient type
Fermentek product
Customs: Other Antibiotics-29419000
Shipped at ambient temperature
Shipped in amber-glass vials
Not considered hazardous for transportation.
Available since
Title
Deprecated CAS
Value
79104-74-8
Fermentek Product Category
Signal to sort
P

Roridin E

Roridin E
Molecular Formula
C29H38O8
M.W.
514.61
CAS number
16891-85-3
MSDS
Source
Myrothecium sp.
Fermentek product Code
ROE-001
Brand/grade
For research
Purity by HPLC
≥ 98% ; refer to CoA for more data
Purity By TLC
≥ 98% ; refer to CoA for more data
Solubility test
Clear colorless solution at 10mg/ml of Dichloromethane or DMSO
Names and identifiers

Synonyms:

  • Roridin E
  • Verrucarin A, 2',3'-didehydro-7'-deoxo-2'-deoxy-7'-(1-hydroxyethyl)-, (2'E,7'R(R))-

Chemical names:

IUPAC:  Verrucarin A, 2',3'-didehydro-7'-deoxo-2'-deoxy-7'-(1-hydroxyethyl)-, (2'E,7'R(R))-(1R,3R,8R,12E,17R,18E,20Z,24R,25S,26S)-17-[(1R)-1-hydroxyethyl]-5,13,25-trimethylspiro[2,10,16,23-tetraoxatetracyclo[22.2.1.03,8.08,25]heptacosa-4,12,18,20-tetraene-26,2'-oxirane]-11,22-dione

T3DB: T3D3711

RTECS# YX9821500

Description

Roridin E is trichothecene toxin produced by molds from Fusarium, Myrothecium, and Stachybotrys genera. 

InChl Key
KEEQQEKLEZRLDS-FLGSVKSYSA-N
Canonical SMILES
CC1=CC2C3(CC1)COC(=O)C=C(CCOC(C=CC=CC(=O)OC4C3(C5(CO5)C(C4)O2)C)C(C)O)C
Isomeric SMILES
CC1=C[C@@H]2[C@@]3(CC1)COC(=O)/C=C(/CCO[C@H](/C=C/C=C\C(=O)O[C@H]4[C@]3([C@]5(CO5)[C@@H](C4)O2)C)[C@@H](C)O)\C
Storage, handling
Store in a freezer upon arrival, at -10°C to -25°C
Open carefully.
Use the original container to store the product.
Keep the lid tightly closed.
Avoid exposing to strong direct light.
Other vendors may recommend higher temperatures for storage.
Protect from moisture!
Retest time
3 years
Disclaimer
For Research use only
Not for Human or Drug use
Not extracted from humans or animals
Refer to MSDS for further safety and handling instructions
Ingredient type
Fermentek product
Shipped in amber-glass vials
Shipped at ambient temperature
Available since

Verrucarin J

Verrucarin J
Molecular Formula
C27H32O8
M.W.
484.54
CAS number
4643-58-7
Source
Myrothecium sp.
Fermentek product Code
VRJ-001
Brand/grade
For research
Appearance
White to faint yellow powder
Purity by HPLC
≥98% ; refer to CoA for more data
Purity By TLC
≥98% ; refer to CoA for more data
Solubility test
Clear colorless to faint yellow solution at 10mg/ml of DMSO or Chloroform
Names and identifiers

Synonyms:

Verrucarin J

Verrucarin A, 2',​3'-​didehydro-​2'-​deoxy-​, (2'E)​-(2'E)-2',3'-Didehydro-2'-deoxyverrucarin

Muconomycin B

Verrucrin J

Verrucosporin J

Chemical names:

Verrucarin A, 2',3'-didehydro-2'-deoxy-

IUPAC:

(1'R,3'R,8'R,12'E,18'E,20'Z,24'R,25'S)-5',13',25'-Trimethyl-11'H,17'H,22'H-spiro[oxirane-2,26'-[2,10,16,23]tetraoxatetracyclo[22.2.1.03,8.08,25]heptacosa[4,12,18,20]tetraene]-11',17',22'-trione

RTECS# YX9822000

EU number
Not on ECHA as on 11-2023
Chemical name
Verrucarin A, 2',3'-didehydro-2'-deoxy-
Merck index
(Verrucarins) M114
Description

 Type D trichothecene, exhibiting anti-cancer properties

InChl Key
GXCGYHWSYNQVHU-UGAPSZEOSA-N
Canonical SMILES
CC1=CC2C3(CC1)COC(=O)C=C(CCOC(=O)C=CC=CC(=O)OC4C3(C5(CO5)C(C4)O2)C)C
Isomeric SMILES
CC1=C[C@@H]2[C@@]3(CC1)COC(=O)/C=C(/CCOC(=O)/C=C/C=C/C(=O)O[C@H]4[C@]3([C@]5(CO5)[C@@H](C4)O2)C)\C
Storage, handling
Store in a freezer upon arrival, at -10°C to -25°C
Open carefully.
Use the original container to store the product.
Keep the lid tightly closed.
Protect from moisture!
Retest time
3 Years
Disclaimer
For Research use only
Not for Human or Drug use
Not extracted from humans or animals
Refer to MSDS for further safety and handling instructions
Ingredient type
Fermentek product
Shipped at ambient temperature

Roridin A

Roridin A
Molecular Formula
C29H40O9
M.W.
532.62
CAS number
14729-29-4
Source
Myrothecium sp.
Fermentek product Code
ROA-001
Brand/grade
For research
Appearance
White to faint yellow powder
Purity by HPLC
≥98% ; refer to CoA for more data
Purity By TLC
≥98% ; refer to CoA for more data
Solubility test
Clear colorless to faint yellow solution at 10mg/ml of DMSO or Chloroform
Names and identifiers

 

Synonyms:

  • Verrucarin A, 7'-deoxo-7'-(1-hydroxyethyl)-
  • Roridin A
  • Roridan A
  • Antibiotic 379X

IUPAC:

(1'R,3'R,8'R,12'S,13'R,17'R,18'E,20'Z,24'R,25'S)-12'-Hydroxy-17'-[(1R)-1-hydroxyethyl]-5',13',25'-trimethyl-11'H,22'H-spiro[oxirane-2,26'-[2,10,16,23]tetraoxatetracyclo[22.2.1.03,8.08,25]heptacosa ;[4,18,20]triene]-11',22'-dione

RTECS# VL0355000

EU number
238-783-8
Description

A type D trichothecene mycotoxin exhibiting anticancer properties

InChl Key
NSFWWJIQIKBZMJ-PAGWOCKZSA-N
Canonical SMILES
CC1CCOC(C=CC=CC(=O)OC2CC3C4(C2(C5(CCC(=CC5O3)C)COC(=O)C1O)C)CO4)C(C)O
Isomeric SMILES
C[C@@H]1CCO[C@H](/C=C/C=C\C(=O)O[C@@H]2C[C@@H]3[C@]4([C@]2([C@]5(CCC(=C[C@H]5O3)C)COC(=O)[C@H]1O)C)CO4)[C@@H](C)O
Compound Classification

Type D Thrichthecene.

Storage, handling
Store in a freezer upon arrival, at -10°C to -25°C
Open carefully.
Use the original container to store the product.
Keep the lid tightly closed.
Other vendors may recommend higher temperatures for storage.
Protect from moisture!
Retest time
3 Years
Applications

Roridin A and other Roridins and Verrucarins are produced by "The Black Mold", a common name for Stachybotrys family of molds that infect houses. Exposure to Roridin A can cause nasal irritation, abundance bodily fluid emission, and harm to the olfactory framework. Gastrointestinal exposure to Roridins can cause ulceration or bleeding from the large intestine, hypermotility, diarrhea. Long-term exposure to Roridins has been reported to cause cognitive disorders.

Roridin A from Fermentek is manufactured using a Myrothecium mold (which belongs to the Stachybotrys family). It is used as a sample to detect Black Mold infection in houses.

Disclaimer
For Research use only
Not for Human or Drug use
Not extracted from humans or animals
Refer to MSDS for further safety and handling instructions
Ingredient type
Fermentek product
Shipped at ambient temperature

Fumonisin B4

Fumonisin B4
Molecular Formula
C34H59NO13
M.W.
689.83
CAS number
136379-60-7
Source
Fusarium moniliforme
Fermentek product Code
FB4-001
Brand/grade
For research
Appearance
White to off white to brown lyophilizate
Purity by HPLC
≥98% ; refer to CoA for more data
Purity By TLC
≥98% ; refer to CoA for more data
Solubility test
Clear colorless to yellow to brown solution at 5mg/ml Methanol or 50mg/ml DMSO
Names and identifiers

Synonyms:

Chemical names:

IUPAC:

(2R,2'R)-2,2'-{[(5R,6R,7S,9S,18S,19S)-19-Amino-18-hydroxy-5,9-dimethyl-6,7-icosanediyl]bis[oxy(2-oxo-2,1-ethanediyl)]}disuccinic acid [ACD/IUPAC Name]

RTECS# TZ8345000

EU number
Not listed as on Aug-2023
Chemical name
(2R,2'R)-2,2'-{[(5R,6R,7S,9S,18S,19S)-19-Amino-18-hydroxy-5,9-dimethyl-6,7-icosanediyl]bis[oxy(2-oxo-2,1-ethanediyl)]}disuccinic acid
Description

 Fumonisin B4 is a mycotoxin of the fumonisin family. It is produced by several Fusarium and Aspergillus species. It is less abundant in the nature than the other three "main" fumonisins.  

InChl Key
WYYKRDVIBOEORL-JLCKPESSSA-N
Canonical SMILES
CCCCC(C)C(C(CC(C)CCCCCCCCC(C(C)N)O)OC(=O)CC(CC(=O)O)C(=O)O)OC(=O)CC(CC(=O)O)C(=O)O
Isomeric SMILES
CCCC[C@@H](C)[C@H]([C@H](C[C@@H](C)CCCCCCCC[C@@H]([C@H](C)N)O)OC(=O)C[C@@H](CC(=O)O)C(=O)O)OC(=O)C[C@@H](CC(=O)O)C(=O)O
Storage, handling
Store in a freezer upon arrival, at -10°C to -25°C
Open carefully.
Use the original container to store the product.
Keep the lid tightly closed.
Avoid exposing to strong direct light.
Other vendors may recommend higher temperatures for storage.
Protect from moisture!
Retest time
3 Years
Disclaimer
For Research use only
Not for Human or Drug use
Not extracted from humans or animals
Refer to MSDS for further safety and handling instructions
Ingredient type
Fermentek product
Shipped at ambient temperature
Available since

Ochratoxin alpha

Ochratoxin alpha
Molecular Formula
C11H9ClO5
M.W.
256.64
CAS number
19165-63-0
Source
Aspergillus ochraceus
Fermentek product Code
OCL-001
Brand/grade
For research
Appearance
Off White powder
Purity by HPLC
≥98% ; refer to CoA for more data
Purity By TLC
≥98% ; refer to CoA for more data
Solubility test
Clear slight yellow solution at 10mg/ml of Methanol
Names and identifiers

Synonyms:

 

  • alpha-Ochratoxin
  • Ochratoxin alpha
  • 5-chloro-8-hydroxy-3,4-dihydro-3-methylisocoumarin-7-carboxylic acid

Chemical names:

IUPAC:

(3R)-5-Chloro-8-hydroxy-3-methyl-1-oxo-3,4-dihydro-1H-isochromene-7-carboxylic acid

RTECS#

EU number
Not on ECHA as on 11-2023
Chemical name
(3R)-5-Chloro-8-hydroxy-3-methyl-1-oxo-3,4-dihydro-1H-isochromene-7-carboxylic acid
Description

Nontoxic metabolite of Ochratoxin A

InChl Key
OSFWJKYWJMZKSM-SCSAIBSYSA-N
Canonical SMILES
CC1CC2=C(C=C(C(=C2C(=O)O1)O)C(=O)O)Cl
Isomeric SMILES
C[C@@H]1CC2=C(C=C(C(=C2C(=O)O1)O)C(=O)O)Cl
Storage, handling
Store in a freezer upon arrival, at -10°C to -25°C
Open carefully.
Use the original container to store the product.
Keep the lid tightly closed.
Other vendors may recommend higher temperatures for storage.
Retest time
3 Years
Applications

OTalpha (OTα) formed by the cleavage of the peptidic bond in OTA is a major metabolite not only in animals and humans, but also in microorganisms and enzyme systems. It is considered as a nontoxic product.

Disclaimer
For Research use only
Not for Human or Drug use
Not extracted from humans or animals
Refer to MSDS for further safety and handling instructions
Ingredient type
Fermentek product
Shipped at ambient temperature

Verrucarin A

Verrucarin A
Molecular Formula
C27H34O9
M.W.
502.55
CAS number
3148-09-2
MSDS
Source
Myrothecium sp.
Fermentek product Code
VRA-001
Brand/grade
For research
Appearance
White to faint yellow powder
Purity by HPLC
≥98% ; refer to CoA for more data
Purity By TLC
≥98% ; refer to CoA for more data
Solubility test
Clear colorless to faint yellow solution at 10mg/ml of DMSO or Chloroform
Names and identifiers

Synonyms:

  • Muconomycin A
  • Spiro[16,18-methano-1H,3H,23H-[1,6,12]trioxacyclooctadecino[3,4-d][1]benzopyran-17(18H),2'-oxirane]-3,9,14-trione, 4,5,6,7,16,16a,19a,22-octahydro-4-hydroxy-5,16a,21-trimethyl-, (4S,5R,10E,12Z,16R,16aS,17S,18R,19aR,23aR)-
  • Verrucarine A

Chemical names:

IUPAC: 

  •  (4S,5R,10E,12Z,16R,16aS,17S,18R,19aR,23aR)-4,5,6,7,16,16a,19a,22-Octahydro-4-hydroxy-5,16a,21-trimethylspiro[16,18-methano-1H,3H,23H-[1,6,12]trioxacyclooctadecino[3,4-d][1]benzopyran-17(18H),2'-oxirane]-3,9,14-trione

Merck index:  M11430  (Verrucarins)

EU number
636-535-7
Description

Verrucarin A is a type D trichothecene  from Stachybotrys, Fusarium, and Myrothecium fungi,  which inhibits protein synthesis and causes apoptosis.

InChl Key
NLUGUZJQJYVUHS-IDXDZYHTSA-N
Canonical SMILES
CC1CCOC(=O)C=CC=CC(=O)OC2CC3C4(C2(C5(CCC(=CC5O3)C)COC(=O)C1O)C)CO4
Isomeric SMILES
C[C@@H]1CCOC(=O)/C=C/C=C\C(=O)O[C@@H]2C[C@@H]3[C@]4([C@]2([C@]5(CCC(=C[C@H]5O3)C)COC(=O)[C@H]1O)C)CO4
Storage, handling
Store in a freezer upon arrival, at -10°C to -25°C
Open carefully.
Use the original container to store the product.
Keep the lid tightly closed.
Avoid exposing to strong direct light.
Other vendors may recommend higher temperatures for storage.
Protect from moisture!
Retest time
3 Years
Disclaimer
For Research use only
Not for Human or Drug use
Not extracted from humans or animals
Refer to MSDS for further safety and handling instructions
Ingredient type
Fermentek product
Transport safety: class 6.1 PG ||
Available since
Title
Depreciated CAS Registry Numbers
Value
11039-36-4 18046-08-7 21462-53-3
Fermentek Product Category

Satratoxin H

Satratoxin H
Molecular Formula
C29H36O9
M.W.
528.59
CAS number
53126-64-0
Source
Stachybotrys chartarum
Fermentek product Code
SAH-001
Brand/grade
For research
Appearance
White to Off-White powder
Purity by HPLC
≥98% ; refer to CoA for more information
Purity By TLC
Single spot on TLC plates, by multiple methods
Solubility test
Clear colorless solution at 10mg/ml of Chloroform Clear colorless solution at 10mg/ml of DMSO
Names and identifiers

Synonyms:

Chemical names:

IUPAC:

(2'R,4E,9R,10E,12Z,16R,16aS,18R,19aR,23aR,25R)-6,7,16,16a,19a,22-

hexahydro-25-hydroxy-9-((1S)-1-hydroxyethyl)-16a,21-dimethyl-spiro(5,9,16,18-dimethano- 1H,3H,23H-(1,6,12)trioxacyclooctadecino(3,4-d)(1)benzopyran-17(18H)-2'-oxirane)- 3,14(9H)-dione

RTECS#  VQ5952000

Depreciated CAS numbers: 54385-59-0, 60538-73-0

 
EU number
Not on ECHA as on 11-2023
Description

Type D highly toxic trichothecene mycotoxin, associated with "sick homes syndrome".

InChl Key
MUACSCLQRGEGOE-RXLTUBJDSA-N
Canonical SMILES
CC1=CC2C3(CC1)COC(=O)C=C4CCOC(C4O)(C=CC=CC(=O)OC5C3(C6(CO6)C(C5)O2)C)C(C)O
Isomeric SMILES
CC1=C[C@@H]2[C@@]3(CC1)COC(=O)C=C4CCO[C@](C4O)(/C=C/C=C/C(=O)O[C@H]5[C@]3([C@]6(CO6)[C@@H](C5)O2)C)[C@H](C)O
Solubility ( literature )

Insoluble in water,
soluble in lower alcohols and polar solvents including

  • methanol,
  • ethanol,
  • isopropanol
  • propylene glycol,
  • acetone,
  • ethyl acetate
  • chloroform,
  • dimethyl sulfoxide
Storage, handling
Store in a freezer upon arrival, at -10°C to -25°C
Hygroscopic substance.
Open carefully.
Use the original container to store the product.
Keep the lid tightly closed.
Avoid exposing to strong direct light.
Other vendors may recommend higher temperatures for storage.
Protect from moisture!
Retest time
3 Years
Disclaimer
For Research use only
Not for Human or Drug use
Not extracted from humans or animals
Refer to MSDS for further safety and handling instructions
Ingredient type
Fermentek product
Shipped at ambient temperature
Available since

Aflatoxin Q1

Aflatoxin Q1
Molecular Formula
C17H12O7
M.W.
328.27
CAS number
52819-96-2
MSDS
Source
Synthetic
Fermentek product Code
AFQ-001
Brand/grade
For research
Appearance
Off White powder
Purity by HPLC
≥98% ; refer to CoA for more data
Purity By TLC
≥98% ; refer to CoA for more data
Solubility test
Clear light yellow solution at 1mg/ml Chloroform
Names and identifiers

Synonyms

  • Cyclopenta[c]furo[3',2':4,5]furo[2,3-h][1]benzopyran-1,11-dione, 2,3,6a,9a-tetrahydro-3-hydroxy-4-methoxy-, (3S,6aR,9aS)-
  • 3-Hydroxy-4-methoxy-2,3,6a,9a-tetrahydrocyclopenta[c]furo[3',2':4,5]furo[2,3-h][1]benzopyran-1,11-dione

 IUPAC Name: 

  • (3S,6aR,9aS)-3-Hydroxy-4-methoxy-2,3,6a,9a-tetrahydrocyclopenta[c]furo[3',2':4,5]furo[2,3-h][1]benzopyran-1,11-dione

RTECS  GY1800000

EU number
637-071-8
Description

Aflatoxin Q1 is a  derivate of Aflatoxin B1. It is created in human body as a in-vivo detoxification process of Aflatoxin B1.

 
InChl Key
GYNOTJLCULOEIM-XKRJZGAWSA-N
Canonical SMILES
COC1=C2C3=C(C(=O)CC3O)C(=O)OC2=C4C5C=COC5OC4=C1
Isomeric SMILES
COC1=C2C3=C(C(=O)C[C@@H]3O)C(=O)OC2=C4[C@@H]5C=CO[C@@H]5OC4=C1
Solubility ( literature )

May be dissolved in DCM, DMSO or Methanol

Compound Classification

Furano-furano-Benzopyran mycotoxin Aflatoxin

Storage, handling
Store in a freezer upon arrival, at -10°C to -25°C
Use the original container to store the product.
Keep the lid tightly closed.
Retest time
3 Years
Disclaimer
For Research use only
Not for Human or Drug use
Not extracted from humans or animals
Refer to MSDS for further safety and handling instructions
Ingredient type
Fermentek product
Shipped at ambient temperature
Shipped in glass vials
Transport safety: class 6.1 PG II
Available since
Title
Transport information
Value
PG
Title
HS FER recommendation
Value
Laboratory reagents or reference material-38220000
Title
toxicity by EC
Value
Acute Tox. 2, H300, H300||Acute Tox. 2, H310, H310||Acute Tox. 2, H330, H330||Carc. 1B, H350, H350
Signal to sort
A

Bongkrekic acid (as solution)

Bongkrekic acid (as solution)
Molecular Formula
C28H38O7
M.W.
486.60
CAS number
11076-19-0
MSDS
Source
Pseudomonas gladioli
Fermentek product Code
BON-001
Brand/grade
For research
Appearance
Clear colorless solution
Purity by HPLC
≥95% ; refer to CoA for more data
Purity By TLC
≥98% ; refer to CoA for more data
Names and identifiers

Synonyms:

  • Bongkrekic Acid
  • Flavotoxin A

Chemical names:

IUPAC:

  • (6R,17S)-20-(carboxymethyl)-6-methoxy-2,5,17-trimethyldocosa-2,4,8,10,14,18,20-heptaenedioic acid

RTECS    

EU number
Not assigned
Chemical name
Bongkrekic acid
Description

Supplied as 1mg/ml solution dissolved in 0.01M Tris buffer pH 7.5. 

InChl Key
SHCXABJSXUACKU-WUTQZGRKSA-N
Canonical SMILES
CC(CC=CCCC=CC=CCC(C(=CC=C(C)C(=O)O)C)OC)C=CC(=CC(=O)O)CC(=O)O
Isomeric SMILES
CC(C/C=C/CC/C=C/C=C\CC(/C(=C\C=C(/C)\C(=O)O)/C)OC)/C=C/C(=C\C(=O)O)/CC(=O)O
Solubility ( literature )
  • Solubility in Water: ~ 1 mg/ml
  • Solubility Notes: ~100 mg/ml in DMSO
Compound Classification
  • Chemical classification:
  • Polyunsaturated tricarboxylic acid

Bioactivity:

  • Glutathione transferase inhibitor
  • ATP/ADP translocase inhibitor
Storage, handling
Store in a freezer upon arrival, at -10°C to -25°C
Protect from light !
Open carefully.
Use the original container to store the product.
Keep the lid tightly closed.
Avoid exposing to strong direct light.
Other vendors may recommend higher temperatures for storage.
Retest time
2 Years
Applications

 Bongcrekic acid is an inhibitor of adenine nucleotide translocator, which inhibits apoptosis, and is thus an important tool for the mechanistic investigation of apoptosis.

Disclaimer
For Research use only
Not for Human or Drug use
Not extracted from humans or animals
Refer to MSDS for further safety and handling instructions
Ingredient type
Fermentek product
Ingredient amount
1 mg/ml in 0.01M Tris buffer pH 7.5
Shipped at ambient temperature
Shipped in PP / PE bottle.
Available since
Title
CAS ambiguity
Value
# 60132-21-0 belongs to Isobongkrekic acid . http://www.molbase.com/en/cas-60132-21-0.html
Title
oral LD50
Value
oral LD50 of the purified Flavotoxin A in mice 3.16 mg/kg
Title
More identity comments; Hu WJ et al; Biomed Environ Sci 2 (1): 65-71 (1989)
Value
Therefore, Flavotoxin A and bongkrekic acid are the same organic chemical compound; the molecular formula is C28H38O7. The oral LD50 of the purified Flavotoxin A in mice was 3.16 mg/kg (1.53-6.15 mg/kg).
Title
Deleted CAS Registry Numbers
Value
11002-93-0, 12715-13-8, 32839-39-7
Title
oral LD50
Value
ANOTHER SOURCE: MOUSE LDL0=6.85 mg/kg PMID:6391376
Signal to sort
B