- NSC 163062
Trisoxireno[4b,5:6,7:8a,9]phenanthro[1,2-c]furan-1(3H)-one, 3b,4,4a,6,6a,7a,7b,8b,9,10-decahydro-6-hydroxy-8b-methyl-6a-(1-methylethyl)-, (3bS,4aS,5aS,6R,6aR,7aS,7bS,8aS,8bS)-
Triptolide is a diterpenoid epoxide which is produced by Tripterygium wilfordii, a vine used in traditional Chinese medicine. Triptolide has pharmacological activities including anti-inflammatory, immune-supressing, antiproliferative anti-angiogenetic, and proapoptotic activity. It has in vitro and in vivo activities against mouse models of polycystic kidney disease and pancreatic cancer.
Reportedly: Insoluble in water. Insoluble in Ethanol. Soluble up to 0.2Molar ( 72 mg/ml) of DMSO
Chemical classification: Terpenoid