Tenuazonic acid – Copper salt
Molecular Formula
C20H28CuN2O6
M.W.
455.99
CAS number
12427-40-6
Source
Alternaria sp.
Fermentek product Code
TNZ-001
Brand/grade
For research
Appearance
Light blue-greenish powder
Purity by HPLC
≥98% ; refer to CoA for more data
Purity By TLC
≥98% ; refer to CoA for more data
Solubility test
Clear blue-green solution at 10mg/ml Dichloromethane
Names and identifiers

Synonyms:

  • 3-Pyrrolin-2-one, 3-acetyl-5-sec-butyl-4-hydroxy-, L-

RTECS: UY7425000
 

 

Description

Tenuazonic acid is a natural mycotoxin, inhibitor of protein synthesis. Tenuazonic acid is offered as its Cuprum salt. 

 

InChl Key
LLXUERDQXVXQAY-UHFFFAOYSA-N
Canonical SMILES
CCC(C)C1C(=C(C(=O)N1)C(=O)C)O.CCC(C)C1C(=C(C(=O)N1)C(=O)C)O.[Cu]
Solubility ( literature )

Soluble in DMSO, pure ethanol, methanol

Compound Classification
  • Pyrrolidinone mycotoxin
  • Tenuazonic Acid Copper Salt is an antineoplastic agent and mycotoxin. It Inhibits protein synthesis, though which it has been shown inhibiting TPA-induced ornithine decarboxylase activity. Lack of ornithine decarboxylase has been shown to eventually cause DNA damage induced apoptosis. It has also been shown to inhibit photosystem II.
Storage, handling
Store in a freezer upon arrival, at -10°C to -25°C
Keep the lid tightly closed.
Avoid exposing to strong direct light.
Other vendors may recommend higher temperatures for storage.
Applications

This is a potential antineoplastic agent

Disclaimer
For Research use only
Not for Human or Drug use
Not extracted from humans or animals
Refer to MSDS for further safety and handling instructions
Semi-Synthetic
Ingredient type
Fermentek product
Available since
Title
Transport information
Value
Pg III
Signal to sort
T