KT5555 (Lestaurtinib)
Molecular Formula
C26H21N3O4
M.W.
439.50
CAS number
111358-88-4
Details
Source
Semisynthetic
Fermentek product Code
LES-001
Brand/grade
For research
Specifications
Appearance
White to off white powder
Purity by HPLC
≥98% ; refer to CoA for more data
Purity By TLC
≥98% ; refer to CoA for more data
Solubility test
Clear colorless solution at 20mg/ml DMSO
Chemical identification
Names and identifiers
IUPAC/Chemical name: (5S,6S,8R)-6-hydroxy-6-(hydroxymethyl)-5-methyl-7,8,14,15-tetrahydro-5H-16-oxa-4b,8a,14-triaza-5,8-methanodibenzo[b,h]cycloocta[jkl]cyclopenta[e]-as-indacen-13(6H)-one
Synonyms
- KT5555
- Lestaurtinib
Description
KT5555 is a multi targeted tyrosine kinase inhibitor.
InChl Key
UIARLYUEJFELEN-LROUJFHJSA-N
Canonical SMILES
CC12C(CC(O1)N3C4=CC=CC=C4C5=C6C(=C7C8=CC=CC=C8N2C7=C53)CNC6=O)(CO)O
Isomeric SMILES
C[C@@]12[C@](C[C@@H](O1)N3C4=CC=CC=C4C5=C6C(=C7C8=CC=CC=C8N2C7=C53)CNC6=O)(CO)O
Further Information
Compound Classification
Chemical classification
- Indole alcaloids - Carbazoles - Staurosporine-derivates
Bioactivity classification
- Enzyme inhibitors
- Proteine kinase inhibitors / Tyrosine kinase inhibitors
Storage, handling
Store in a freezer upon arrival, at -10°C to -25°C
Protect from light !
Use the original container to store the product.
Keep the lid tightly closed.
Store under argon.
Retest time
3 Years
Applications
It is used for the treatment of pancreatic cancer and acute myelogenous leukaemia (AML).
Disclaimer
For Research use only
Not for Human or Drug use
Not extracted from humans or animals
Refer to MSDS for further safety and handling instructions
Semi-Synthetic
Composition
Ingredient type
Fermentek product
Special Info
Available since
Other Fields
Title
Transport information
Value
Not hazardous for transport
Title
CN code
Value
29349990
Title
CN code
Value
NO!!!
Title
inert gas storage
Value
after merck, TRC, carbosynth
Fermentek Product Category
Signal to sort
K
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