HC toxin
Molecular Formula
C21H32N4O6
M.W.
436.50
CAS number
83209-65-8
MSDS
Details
Source
Helminthosporium carbonum
Fermentek product Code
HCT-001
Brand/grade
For research
Specifications
Appearance
White lyophilized powder
Purity by HPLC
≥98% ; refer to CoA for more data
Purity By TLC
≥98% ; refer to CoA for more data
Solubility test
Clear colorless solution at 10mg/ml of Acetonitrile
Chemical identification
Names and identifiers
Synonyms:
- HC-Toxin
-
Helminthosporium Carbonum Toxin I
Chemical names:
IUPAC: (3S,6R,9S,14aR)-3,6-Dimethyl-9-{6-[(2S)-2-oxiranyl]-6-oxohexyl}decahydropyrrolo[1,2-a][1,4,7,10]tetraazacyclododecine-1,4,7,10-tetrone
RTECS#
EU number
804-302-0
Chemical name
Cyclo(2-amino-8-oxo-9,10-epoxydecanoic acid-prolyl-alanyl-alanine)
Description
Cyclic tetrapeptide of structure cyclo(D-Pro-L-Ala-D-Ala-L-Aeo), where Aeo stands for 2-amino-9,10-epoxi-8-oxodecanoic acid. HC toxin is a potent, cell-permeable inhibitor of histone deacetylase (HDAC).
InChl Key
GNYCTMYOHGBSBI-KVUCBBCISA-N
Canonical SMILES
CC1C(=O)NC(C(=O)N2CCCC2C(=O)NC(C(=O)N1)C)CCCCCC(=O)C3CO3
Isomeric SMILES
C[C@@H]1C(=O)N[C@H](C(=O)N2CCC[C@@H]2C(=O)N[C@H](C(=O)N1)C)CCCCCC(=O)C3CO3
Further Information
Compound Classification
Cyclic oligopeptide
Storage, handling
Store in a freezer upon arrival, at -10°C to -25°C
Open carefully.
Use the original container to store the product.
Keep the lid tightly closed.
Avoid exposing to strong direct light.
Other vendors may recommend higher temperatures for storage.
Disclaimer
For Research use only
Not for Human or Drug use
Not extracted from humans or animals
Refer to MSDS for further safety and handling instructions
Composition
Ingredient type
Fermentek product
Special Info
Available since
Other Fields
Title
Deleted CAS Registry Numbers
Value
82653-17-6; 89363-02-0; 110114-88-0
Fermentek Product Category
Signal to sort
H
