Enniatin A

Molecular Formula:

C36H63N3O9

CAS number:

2503-13-1

Fermentek product code:

ENA

Source:

Fusarium sp.

Brand/grade:

For research

Specifications

Appearance:

White powder

Purity by HPLC:

≥ 97% ; refer to CoA for more data

Purity By TLC:

≥98% by multiple methods; refer to CoA for details

Melting point:

121°C-125°C

Solubility test:

Clear colorless solution at 10mg/ml of Dichloromethane or Methanol

Chemical identification

Names and identifiers:

Synonyms:

Chemical names: Fusafungine ; Enniatin-A

IUPAC: (3S,9S,12R,15S,18R)-9,15-bis[(2S)-butan-2-yl]-3-[(2R)-butan-2-yl]-4,10,16-trimethyl-6,12,18-tri(propan-2-yl)-1,7,13-trioxa-4,10,16-triazacyclooctadecane-2,5,8,11,14,17-hexone

A Fusarium produced depsipeptide ionophore

RTECS#

Condensed IUPAC: cyclo[N(Me)Ile-D-OVal-N(Me)Ile-DL-OVal-N(Me)aIle-D-OVal]

EU number:

215-737-5

Description:

Enniatin A is a least abundant commponent of the Enniatin-complex. It has been recently made available as a pure compound, thanks to the most advanced preparative HPLC methods.

Molecular weight:

681.90

InChl Key:

TWHBYJSVDCWICV-BHZTXFQCSA-N

Canonical SMILES:

CCC(C)C1C(=O)OC(C(=O)N(C(C(=O)OC(C(=O)N(C(C(=O)OC(C(=O)N1C)C(C)C)C(C)CC)C)C(C)C)C(C)CC)C)C(C)C

Isomeric SMILES:

CC[[email protected]](C)[[email protected]]1C(=O)O[[email protected]@H](C(=O)N([[email protected]](C(=O)O[[email protected]@H](C(=O)N([[email protected]](C(=O)O[[email protected]@H](C(=O)N1C)C(C)C)[[email protected]@H](C)CC)C)C(C)C)[[email protected]@H](C)CC)C)C(C)C

Further Information

Solubility ( literature ):

Soluble in ethanol, methanol, DMSO, DMF.

Compound Classification:

Chemical classification: Cyclic depsipeptide.

Biological classification:

Storage, handling:

Store in a freezer upon arrival, at -10°C to -25°C

Protect from moisture

Open carefully.

Use the original container to store the product.

Keep the lid tightly closed.

Avoid exposing to strong direct light.

Other vendors may recommend higher temperatures for storage.

Applications:

Natural enniatins occure as a mixture of several related analogs, known as "Enniatins", or "Enniatin complex".

Enniatins occure in nature in the mycelia of some Fusarium species. Being cyclic and hydrophopic molecules, enniatins are able to act as ionophores. More recently their effects on acyl-CoA cholesterol transferase, transporters and the selectivity of their antitumor action have received more focus. Enniatin has not previously been available for investigation.

Disclaimer:

For Research use only

Not for Human or Drug use

Not extracted from humans or animals

Refer to MSDS for further safety and handling instructions