Trichostatin A
Molecular Formula
C17H22N2O3
M.W.
302.37
CAS number
58880-19-6
Source
Streptomyces platensis
Fermentek product Code
TRA-001
Brand/grade
For research
Appearance
White to Off-White powder
Purity by HPLC
≥98% ; refer to CoA for more data
Purity By TLC
≥98% ; refer to CoA for more data
Melting point
138°C-150°C
Solubility test
Clear colorless solution at 5mg/ml Methanol; Clear yellow solution at 20mg/ml DMSO
Names and identifiers

Synonyms:

  • 2,​4-​Heptadienamide, 7-​[4-​(dimethylamino)​phenyl]​-​N-​hydroxy-​4,​6-​dimethyl-​7-​oxo-​, (2E,​4E,​6R)​-
  • (2E,4E,6R)-7-[4-(Dimethylamino)phenyl]-N-hydroxy-4,6-dimethyl-7-oxo-2,4-heptadienamide
  • TSA
  • (R)-(+)-Trichostatin A

 

 

EU number
611-758-2
Description

Trichostatin A is an antifungal antibiotic.

Trichostatin A is a potent, reversible inhibitor of histone deacetylase (HDAC)

InChl Key
RTKIYFITIVXBLE-QEQCGCAPSA-N
Canonical SMILES
CC(C=C(C)C=CC(=O)NO)C(=O)C1=CC=C(C=C1)N(C)C
Isomeric SMILES
C[C@H](/C=C(\C)/C=C/C(=O)NO)C(=O)C1=CC=C(C=C1)N(C)C
Solubility ( literature )

DMSO, Ethanol

Compound Classification

HDAC inhibitor

Storage, handling
Store in a freezer upon arrival, at -10°C to -25°C
Protect from moisture
Open carefully.
Use the original container to store the product.
Avoid exposing to strong direct light.
Other vendors may recommend higher temperatures for storage.
Disclaimer
For Research use only
Not for Human or Drug use
Not extracted from humans or animals
Refer to MSDS for further safety and handling instructions
Ingredient type
Fermentek product
Available since
Title
Transport information
Value
Not hazardous for transport
Signal to sort
T