IUPAC name: (1aR,4E,7aS,10aS,10bS)-1a,5-Dimethyl-8-methylene-2,3,6,7,7a,8,10a,10b-octahydrooxireno[9,10]cyclodeca[1,2-b]furan-9(1aH)-one
Parthenolide is a sesquiterpene lactone and active principle of feverfew (Chrysanthemum parthenium)
DMSO (100 mg/ml), Ethanol (20 mg/ml), Dichloromethane.
- sesquiterpene lactone
MAP kinase inhibitor
Parthenolide has anti-inflammatory, antisecretory and spasmolytic activity. It Inhibits the release of various mediators. It inhibits activation of MAP kinase.