Meleagrin, a fungal alcaloide antibiotic, posesses antitumor and antibiotic activity. Meleagrin has been identified as an inhibitor of the bacterial enoyl-acyl carrier protein reductase.
Meleagrin, CAS 71751-77-4, the fungal alcaloide, should not be confused with the low molecular weight peptide cas 121272-63-7, which is isolated from turkey also called meleagrin.
Ethanol, methanol, DMF or DMSO. Poor water solubility
Inhibitor of: Enoyl-[acyl-carrier-protein] reductase [NADH] FabI
J Antibiot (Tokyo). 2010 Apr;63(4):165-70.
Alkaloids from a deep ocean sediment-derived fungus Penicillium sp. and their antitumor activities.
Du L, Feng T, Zhao B, Li D, Cai S, Zhu T, Wang F, Xiao X, Gu Q.