Equisetin

Molecular Formula:

C22H31NO4

CAS number:

57749-43-6

EU number:

303-396-6

Fermentek product code:

Source:

Fusarium equiseti

Brand/grade:

For research

Specifications

Appearance:

Light tan to tan or off-white powder

Purity by HPLC:

≥98% ; refer to CoA for more data

Purity By TLC:

≥98% ; refer to CoA for more data

Solubility test:

Clear colorless solution at 10 mg/ml of Methanol or DMSO

Chemical identification

Names and identifiers:

IUPAC:

(2S)-4-({(1S,2R,4aS,6R,8aR)-1,6-Dimethyl-2-[(1E)-1-propen-1-yl]-1,2,4a,5,6,7,8,8a-octahydro-1-naphthalenyl}carbonyl)-5-hydroxy-2-(hydroxymethyl)-1-methyl-1,2-dihydro-3H-pyrrol-3-one

RTECS KD7986000

Description:

Antibiotic from Fusarium equiseti; derivative of N-methyl-2,4-pyrollidone

Molecular weight:

373.49

InChl Key:

QNQBPPQLRODXET-HMHJLHGTSA-N

Canonical SMILES:

CC=CC1C=CC2CC(CCC2C1(C)C(=C3C(=O)C(N(C3=O)C)CO)O)C

Isomeric SMILES:

C/C=C/[[email protected]@H]1C=C[[email protected]@H]2C[[email protected]@H](CC[[email protected]]2[[email protected]]1(C)/C(=C\3/C(=O)[[email protected]@H](N(C3=O)C)CO)/O)C

Further Information

Solubility ( literature ):

Equisetin is reported to be soluble in DMF or DMSO, moderately soluble in methanol or ethanol and poorly soluble in water.

Equisetin solubility as reported in an original patent,

in acetone of 660 mg./ml.,
in ethanol of 330 mg./ml.,
in methanol of 220 mg./ml.,
in hexane of 0.8 mg./ml.,
in water of 0.3 mg./ml.

Elemental analysis: C, 70.95; H, 8.39; N, 3.14;

Compound Classification:

Chemical classification:

Tetramic acid class antibiotic.

Classification by Bioactivity:

HIV-integrase inhibitor

Storage, handling:

Store in a freezer upon arrival, at -10°C to -25°C

Use the original container to store the product.

Keep the lid tightly closed.

Avoid exposing to strong direct light.

Other vendors may recommend higher temperatures for storage.

Applications:

Equisetin inhibits some ATPases, and affects several energy related mitochondrial enzymes.Equisetin was also shown to inhibit (in-vitro) HIV-1 integrase.

Disclaimer:

For Research use only

Not for Human or Drug use

Not extracted from humans or animals

Refer to MSDS for further safety and handling instructions

Composition

Ingredient type:

Fermentek product

Supply related information

Supply related comments:

Amber-glass vial.

Special Info

Available since:

2016

Other Fields

Title:

Transport

Value:

Not regulated

Title:

Animal rawmat

Value: