Castanospermine

Castanospermine
Molecular Formula
C8H15NO4
M.W.
189.21
CAS number
79831-76-8
Source
Castanospermum australe (plant extract)
Fermentek product Code
CAS-001
Brand/grade
For research
Appearance
White to off-white solid.
Purity By TLC
≥98% ; refer to CoA for more data
Melting point
202°C-215°C
Names and identifiers

Synonyms:

  • 1,6,7,8-Tetrahydroxyoctahydroindolizine
EU number
616-743-4
Description

Alkaloid extracted from an australian legume. Potent inhibitor of α- and β-glucosidase activity in fibroblast extracts; inhibits the glycoprotein processing cycle. Exhibits antiviral properties. Inhibits angiogenesis.

InChl Key
JDVVGAQPNNXQDW-TVNFTVLESA-N
Canonical SMILES
C1CN2CC(C(C(C2C1O)O)O)O
Isomeric SMILES
C1CN2C[C@@H]([C@H]([C@@H]([C@H]2[C@H]1O)O)O)O
Solubility ( literature )

Soluble in water.

Compound Classification

Indolizidine alkaloid

Glycosidase Inhibitor

Angiogenesis inhibitor

Storage, handling
Store in a freezer upon arrival, at -10°C to -25°C
Open carefully.
Other vendors may recommend higher temperatures for storage.
Retest time
3 Years
Applications

Potent inhibitor of α- and β-glucosidases. 
Inhibits HIV infectivity. 
Inhibits angiogenesis. 
Inhibits thyroglobulin secretion. 
Antitumor activty. 
Inhibits protein glycosylation.

Disclaimer
Refer to MSDS for further safety and handling instructions.
Ingredient type
Fermentek product
Available since