- (2S,3R,4R,6E)-2-Amino-3,4-dihydroxy-2-(hydroxymethyl)-14-oxo-6-eicosenoic acid
Fungal antibiotic, atypic amino acid, immunomodulator, serine palmitoyltransferase inhibitor, apoptosis inducer.
Myriocin is slightly soluble in DMSO, alcohols.Myriocin is insoluble in water and in most organic solvents.
- amino-acid antibiotic
- serine palmitoyltransferase inhibitor
Myriocin, a potent inhibitor of serine palmitoyltransferase,a (the 1st step in sphingosine biosynthesis), is used in biochemical research as a tool for depleting cells of sphingolipids. Myriocin is a potent immunosuppressor, reportedly 10 to 100 times stronger than cyclosporin.