- Brefeldin A
EC# : 606-528-3
Brefeldin A is a macrocyclic lactone from Penicillium brefeldiana, exhibiting a wide range of antibiotic activity.
It is currently used in research mainly as an assay tool for studying membrane traffic and vesicle transport dynamics between the endoplasmic reticulum and Golgi apparatus.
Methanol, Ethanol, Dichloromethane, DMSO, acetone or ethyl acetate
- Macrocyclic lactone antibiotic.
- Protein Synthesis Inhibitor
Inhibitor of protein translocation from endoplasmic reticulum (ER) to the Golgi apparatus.
Inhibitor of intracellular protein transport and protein secretionA macrolide isolated from Penicillium brefeldianum. It affects the vesticular transport of the Golgi apparatus and induces DNA fragmentation which leads to apoptosis.