Aflatoxin B1

Molecular Formula:

C17H12O6

CAS number:

1162-65-8

EU number:

214-603-3

Fermentek product code:

Source:

Aspergillus flavus

Brand/grade:

For research

Specifications

Appearance:

White to faint yellow powder

Purity by HPLC:

≥98% ; refer to CoA for more data

Purity By TLC:

≥98% ; refer to CoA for more data

Solubility test:

Clear colorless solution at 10mg/ml of Dichloromethane

Chemical identification

Names and identifiers:

2,3,6aα,9aα-tetrahydro-4-methoxycyclopenta[c]furo[2',3':4,5]furo[2,3-h]chromene-1,11-dione

HSDB 3453

Description:

Aflatoxin B1 is a Food-contaminant, regulated in most countries from Fermentek_Ltd is used by dedicated laboratories as a reference material, necessary to detect contamination in food and feed stuffs. Aflatoxin B1 is a potent hepatotoxic and hepatocarcinogenic mycotoxin. It is also mutagenic, teratogenic, and causes immunosuppression in animals.

Molecular weight:

312.27

InChl Key:

OQIQSTLJSLGHID-WNWIJWBNSA-N

Canonical SMILES:

COC1=C2C3=C(C(=O)CC3)C(=O)OC2=C4C5C=COC5OC4=C1

Isomeric SMILES:

COC1=C2C3=C(C(=O)CC3)C(=O)OC2=C4[C@@H]5C=CO[C@@H]5OC4=C1

Further Information

Solubility ( literature ):

May be dissolved in DCM, DMSO or Methanol LD50 - Lethal dose, 50 percent killOralPrimate - monkey2200 ug/kgBehavioral - somnolence (general depressed activity)TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 19,169,1971LD50 - Lethal dose, 50 percent killOralRodent - mouse9 mg/kgDetails of toxic effects not reported other than lethal dose valueENTOX* Encyclopedia of Toxicology: Reference Book, Elsevier, 2005 Volume(issue)/page/year: -,177,2005 TDLo - Lowest published toxic doseOralRodent - rat5 mg/kgfemale 16 day(s) after conceptionReproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)BJEPA5 British Journal of Experimental Pathology. (Blackwell Scientific Pub. Ltd., POB 88, Oxford, UK) V.1- 1920- Volume(issue)/page/year: 47,242,1966

Compound Classification:

Furano-furano-Benzopyran mycotoxin Aflatoxin

Storage, handling:

Store in a freezer upon arrival, at -10°C to -25°C

Use the original container to store the product.

Keep the lid tightly closed.

Open carefully – Lyophilized solid under vacuum

Retest time:

Composition

Ingredient type:

Fermentek product

Supply related information

Supply related comments:

Customs: Laboratory reagents-38220000

Shipped at ambient temperature

Shipped in amber-glass vials

This compound is on the Dual Use list. An import permit may be needed

Transport safety: class 6.1 (Poison) PG I

Transport safety: class 6.1 PG I

Publications

Production of aflatoxin by the culture of strains of Aspergillus flavus-oryzae on sterilized peanuts.
Codner, R. C.; Sargeant, K.; Yeo, R. Microbiol. Res. Estab., Porton,
UK. Biotechnology and Bioengineering (1963), 5 185-92.

Aflatoxin B1 contamination in maize in Europe increases due to climate change
P. Battilani, P. Toscano, H. J. Van der Fels-Klerx, A. Moretti, M. Camardo Leggieri, C. Brera, A. Rortais, T. Goumperis & T. Robinson
Scientific Reports volume 6, Article number: 24328 (2016)

Special Info

Available since:

2003

Other Fields

Title:

Transport information

Value:

PG I

Title:

HS FER recommendation

Value:

Laboratory reagents or reference material-38220000

Title:

HS--EU

Value:

Heterocyclic compounds wi/ oxygen hetero-atom(s) only; lactones; other

Title:

targers

Value:

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