Specifications
Chemical identification
2,3,6aα,9aα-tetrahydro-4-methoxycyclopenta[c]furo[2',3':4,5]furo[2,3-h]chromene-1,11-dione
HSDB 3453
Aflatoxin B1 is a Food-contaminant, regulated in most countries from Fermentek_Ltd is used by dedicated laboratories as a reference material, necessary to detect contamination in food and feed stuffs. Aflatoxin B1 is a potent hepatotoxic and hepatocarcinogenic mycotoxin. It is also mutagenic, teratogenic, and causes immunosuppression in animals.
Further Information
May be dissolved in DCM, DMSO or Methanol LD50 - Lethal dose, 50 percent killOralPrimate - monkey2200 ug/kgBehavioral - somnolence (general depressed activity)TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 19,169,1971LD50 - Lethal dose, 50 percent killOralRodent - mouse9 mg/kgDetails of toxic effects not reported other than lethal dose valueENTOX* Encyclopedia of Toxicology: Reference Book, Elsevier, 2005 Volume(issue)/page/year: -,177,2005 TDLo - Lowest published toxic doseOralRodent - rat5 mg/kgfemale 16 day(s) after conceptionReproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)BJEPA5 British Journal of Experimental Pathology. (Blackwell Scientific Pub. Ltd., POB 88, Oxford, UK) V.1- 1920- Volume(issue)/page/year: 47,242,1966
Furano-furano-Benzopyran mycotoxin Aflatoxin
Composition
Supply related information
Publications
Production of aflatoxin by the culture of strains of Aspergillus flavus-oryzae on sterilized peanuts.
Codner, R. C.; Sargeant, K.; Yeo, R. Microbiol. Res. Estab., Porton,
UK. Biotechnology and Bioengineering (1963), 5 185-92.
Aflatoxin B1 contamination in maize in Europe increases due to climate change
P. Battilani, P. Toscano, H. J. Van der Fels-Klerx, A. Moretti, M. Camardo Leggieri, C. Brera, A. Rortais, T. Goumperis & T. Robinson
Scientific Reports volume 6, Article number: 24328 (2016)