Celastrol (Tripterin)
Molecular Formula
C29H38O4
M.W.
450.61
CAS number
34157-83-0
MSDS
Source
Tripterygium wilfordii
Fermentek product Code
CEL-001
Brand/grade
For research
Appearance
Red powder
Purity by HPLC
≥98% ; refer to CoA for more data
Purity By TLC
≥98% ; refer to CoA for more data
Melting point
190°C-220°C
Solubility test
Clear red solution at 10mg/ml DMSO,
Clear red solution at 10mg/ml Ethanol
Names and identifiers

Synonyms:

  • Tripterin
  • Celastrol

Chemical names:

RTECS: YJ7900000

 
EU number
636-472-5
Description

Celastrol is a chemical compound isolated from the root extracts of Tripterygium wilfordii and Celastrus regelii. Celastrol is a pentacyclic triterpenoid and belongs to the family of quinone methides. In mice, celastrol increases expression of IL1R1, which is the receptor for the cytokine interleukin-1. Celastrol is an antioxidant, anti-inflammatory and immunosuppressive agent. 

InChl Key
KQJSQWZMSAGSHN-JJWQIEBTSA-N
Canonical SMILES
CC1=C(C(=O)C=C2C1=CC=C3C2(CCC4(C3(CCC5(C4CC(CC5)(C)C(=O)O)C)C)C)C)O
Isomeric SMILES
CC1=C(C(=O)C=C2C1=CC=C3C2(CCC4(C3(CCC5(C4CC(CC5)(C)C(=O)O)C)C)C)C)O
Storage, handling
Store in a freezer upon arrival, at -10°C to -25°C
Open carefully.
Use the original container to store the product.
Keep the lid tightly closed.
Avoid exposing to strong direct light.
Other vendors may recommend higher temperatures for storage.
Protect from moisture!
Retest time
3 Years
Disclaimer
For Research use only
Not for Human or Drug use
Not extracted from humans or animals
Refer to MSDS for further safety and handling instructions
Ingredient type
Fermentek product
Shipped at ambient temperature
Shipped in PP / PE bottle.
Transport safety: Not Dangerous Goods; Not Regulated
Available since