Wortmannin is an antifungal antibiotic, similar to Viridin.
DMSO, Methanol. Wortmannin is unstable in aqueous and ethanolic solutions.
- chemical class:Androstadiene
- phospholipase D inhibitor.
Wortmannin is an inhibitor of phosphatidyl-inositol 3-kinase Wortmannin inhibits the growth of mammary tumors despite the existence of a novel wortmannin-insensitive phosphatidylinositol-3-kinase. Wortmannin inhibits repair of DNA double-strand breaks in irradiated normal human cells. Wortmannin was shown to have enhancing influence on memory and impair learning abilities. .