Lovastatin/Mevinolin is a strong inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase. That enzyme controls biosynthesis of Cholesterol in liver. Also inhibits MAP kinase and p21ras activation
Chloroform - up to 35% w/v ; Acetone up to 4% w/v, Acetonitrile up to 3% w/v Slightly soluble in water (less than 0.5% w/v)
- Statin antibiotic
- Apoptosis inducer
Lovastatin has been reported to cause cell cycle arrestLovastatin was reported to induce apoptosis in several lines of cancer cells.