- 17-(Allylamino)-17-demethoxy- geldanamycin
17AAG, also known as "Tanespimycin", is an ansamycin antibiotic which binds to Hsp90 (Heat Shock Protein 90) and alters it function.
17AAG is less hepatotoxic than Geldanamycin.
DMSO, Methanol. The solubility of 17-AAG in DMSO is >10 mM. General tips for obtaining a higher concentration: Heating to 37°C and using ultrasonic bath is advisable.
- Benzoquinone ansamycin antibiotic.
- Geldanamycin derivate.
- HSP90 inhibitor.
This compound was mentioned as an anticancer medicine. Geldanamycin derivates all interfere with heat-shock proteins, especially HSP90. 17-AAG belongs to a class of drugs called heat shock protein 90 (Hsp90) inhibitors.