Ergotamine

Molecular Formula:

C33H35N5O5

CAS number:

113-15-5

Fermentek product code:

Brand/grade:

For research

Specifications

Purity by HPLC:

Beige powder

Purity By TLC:

>99% in multiple test conditions; for particular lot data refer to the CoA of that lot.

Melting point:

180 - 182°C

Solubility test:

Clear colorless solution at 10 mg/ml methanol.

Chemical identification

Names and identifiers:

synonyms

Ergotamine
Ergotamine Tartrate
Ergotaminine
Gynergen

EU number:

204-023-9

Description:

A vasoconstrictor found in ergot of Central Europe. It is an alpha-1 selective adrenergic agonist and is commonly used in the treatment of migraine disorders

Molecular weight:

581.66

InChl Key:

XCGSFFUVFURLIX-VFGNJEKYSA-N

Canonical SMILES:

CC1(C(=O)N2C(C(=O)N3CCCC3C2(O1)O)CC4=CC=CC=C4)NC(=O)C5CN(C6CC7=CNC8=CC=CC(=C78)C6=C5)C

Isomeric SMILES:

C[C@@]1(C(=O)N2[C@H](C(=O)N3CCC[C@H]3[C@@]2(O1)O)CC4=CC=CC=C4)NC(=O)[C@H]5CN([C@@H]6CC7=CNC8=CC=CC(=C78)C6=C5)C

Further Information

Solubility ( literature ):

reportedly: Soluble in about 70 parts methanol, 150 parts acetone, 300 parts alcohol; freely soluble in chloroform, pyridine, glacial acetic acid; moderately soluble in ethyl acetate; slightly soluble in benzene; almost insoluble in petroleum ether. Slightly soluble in water.

Compound Classification:

Ergot Alkaloid
serotonin agonist
vasoconstrictor
Non-Narcotic Analgesic

Storage, handling:

Store in a freezer upon arrival, at -10°C to -25°C

Use the original container to store the product.

Keep the lid tightly closed.

Avoid exposing to strong direct light.

Protect from moisture! Hygroscopic substance.

Applications:

vasoconstrictor Vasoconstrictor agent; An agent that has an affinity for serotonin receptors and is able to mimic the effects of serotonin by stimulating the physiologic activity at the cell receptors. Serotonin agonists are used as antidepressants, anxiolytics, and in the treatment of migraine disorders. Drug precursor.

Disclaimer:

For Research use only

Not for Human or Drug use

Not extracted from humans or animals

Refer to MSDS for further safety and handling instructions

Composition

Ingredient type:

Fermentek product

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Import license is needed