IUPACK name: 8,12-Epoxy-1H,8H-2,7b,12a-triazadibenzo(a,g)cyclonona(cde)trinden-1-one, 2,3,9,10,11,12-hexahydro-9-methoxy-8-methyl-10-(methylamino)-, (8alpha,9beta,10beta,12alpha)-(+)-
Staurosporine is a cell permeable inhibitor of protein kinases, including protein kinase-C.
DMSO, Methanol, Ethanol, Ethyl Acetate. Water insoluble
Chemical classification: Indolocarbazole alkaloid
Bio-activity: PKC inhibitor
Pharmacological tool to study signal transduction pathways, tyrosine phosphorylation and to induce apoptosis.
May participate in antigen-induced T-cell activation;
Affects Proto-oncogene serine/threonine-protein kinase Pim-1, T-cell-specific kinase, Tyrosine-protein kinase SYK, MAP kinase-activated protein kinase 2