Phorbol related diterpene ester; potent agonist of vanilloid TRPV1 receptors. Resiniferatoxin (RTX) is a naturally occurring, ultrapotent capsaicin analog that activates the vanilloid receptor in sensory neurons involved in transmission of pain signals.
Insoluble in water. Soluble in DCM, Methanol, Ethanol
- vanilloid receptoractivator
- PKC activator
Resiniferatoxin has been used to label the vanilloid receptor in sensory ganglia. Resiniferatoxin has been report to stimulate PKC (protein kinase C)